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ALDB: A Domestic-Animal Long Noncoding RNA Database
文献类型：期刊论文
| 作者 | Li AM1,2; Zhang JY[*]1; Zhou ZY3,4; Wang L2; Liu YJ5; Liu YJ1,6 |
| 刊名 | PLOS ONE
 |
| 出版日期 | 2015 |
| 卷号 | 10期号:4页码:e0124003 |
| 通讯作者 | jyzhang@mail.xidian.edu.cn |
| 合作状况 | 其它 |
| 英文摘要 | Background Long noncoding RNAs (lncRNAs) have attracted significant attention in recent years due to their important roles in many biological processes. Domestic animals constitute a unique resource for understanding the genetic basis of phenotypic variation and are ideal models relevant to diverse areas of biomedical research. With improving sequencing technologies, numerous domestic-animal lncRNAs are now available. Thus, there is an immediate need for a database resource that can assist researchers to store, organize, analyze and visualize domestic-animal lncRNAs. Results The domestic-animal lncRNA database, named ALDB, is the first comprehensive database with a focus on the domestic-animal lncRNAs. It currently archives 12,103 pig intergenic lncRNAs (lincRNAs), 8,923 chicken lincRNAs and 8,250 cow lincRNAs. In addition to the annotations of lincRNAs, it offers related data that is not available yet in existing lncRNA databases (lncRNAdb and NONCODE), such as genome-wide expression profiles and animal quantitative trait loci (QTLs) of domestic animals. Moreover, a collection of interfaces and applications, such as the Basic Local Alignment Search Tool (BLAST), the Generic Genome Browser (GBrowse) and flexible search functionalities, are available to help users effectively explore, analyze and download data related to domestic-animal lncRNAs. Conclusions ALDB enables the exploration and comparative analysis of lncRNAs in domestic animals. A user-friendly web interface, integrated information and tools make it valuable to researchers in their studies. |
| 资助信息 | This work was supported by the Natural Science Foundation of China (http://www.nsfc.gov.cn/) under Grants 61070137, 91130006,61201312 and 61303122; and the Research Fund for the Doctoral Program of Higher Education of China (http://www. moe.edu.cn/, 20130203110017); and the Fundamental Research Funds for the Central Universities of China (http://www.moe.edu.cn/, BDY171416 and JB140306). |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000352478400129 |
| 公开日期 | 2015-05-11 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8327]  |
| 专题 | 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.School ofComputerScienceand Technology, Xidian University, Xi'an, Shaanxi,PRChina 2.School of ComputerScienceand Engineering,Xi'anUniversity ofTechnology, Xi'an,Shaanxi,PR China 3.Department ofMolecular and CellBiology, School ofLifeSciences,University ofScience and Technology ofChina,Hefei, PR China 4.State Key Laboratory ofGeneticResources and Evolution, Kunming Institute ofZoology, Chinese Academy ofSciences, Kunming,PR China 5.Xi'anDongXing Branch,CMSTDevelopment Co.Ltd., Xi'an, Shaanxi, PR China 6.HigherTechnology College,Xi'anUniversity ofTechnology, Xi'an, Shaanxi,PRChina |
| 推荐引用方式 GB/T 7714 | Li AM,Zhang JY[*],Zhou ZY,et al. ALDB: A Domestic-Animal Long Noncoding RNA Database[J]. PLOS ONE,2015,10(4):e0124003. |
| APA | Li AM,Zhang JY[*],Zhou ZY,Wang L,Liu YJ,&Liu YJ.(2015).ALDB: A Domestic-Animal Long Noncoding RNA Database.PLOS ONE,10(4),e0124003. |
| MLA | Li AM,et al."ALDB: A Domestic-Animal Long Noncoding RNA Database".PLOS ONE 10.4(2015):e0124003. |
入库方式： OAI收割
来源：昆明动物研究所
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