Hantaviruses in Small Mammals and Humans in the Coastal Region of Zhejiang Province, China
文献类型:期刊论文
作者 | Zhang YZ[*]1,2; Lin XD2,3; Guo WP2; Fan FN4; Huang XM6; Li MH6; Li MF3; Chen Y3; Shi NF4; Chen XP3 |
刊名 | JOURNAL OF MEDICAL VIROLOGY
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出版日期 | 2010 |
卷号 | 82期号:6页码:987-995 |
关键词 | hemorrhagic fever with renal syndrome hantavirus Seoul virus |
通讯作者 | yongzhenzhang@sohu.com |
合作状况 | 其它 |
英文摘要 | To gain more insights into the epidemiology of hantaviruses in the coastal region of Zhejiang Province, China, the morbidity and mortality of hemorrhagic fever with renal syndrome (HFRS) were analyzed in two coastal areas. Cixi (hilly terrain) and Wenzhou (mountainous terrain). More HFRS cases have been reported in Cixi than in Wenzhou. Annual incidence rate of HERS in Cixi had been on the level of approximately 1 5/100,000 from 1968 (when the first HFRS case was reported) to 2007, with the highest incidence rate of 8.54/100,000 in 1999. The annual incidence rate in Wenzhou has been relatively low, less than 0 5/100,000 since the first HFRS case was reported in 1981. A total of 461 rodents and 199 shrews were captured in these two areas. Hantavirus antibodies were detected in 16 of 241 (6.64%) Rattus norvegicus and 13 of 122(10.66%) R. flavipectus Interestingly, hantavirus antigens were identified in 6 of 196 (3.06%) Suncus murinus. Genetic analysis showed that partial M and S segment sequences recovered from rats in the two regions belong to Seoul virus (SEOV) and can be assigned into two genetic lineages. SEOV variants that belong to these two lineages of viruses are distributed widely in China and have been found outside China. As most trapped rodents were rats and SEOV was the only hantavirus detected, these results suggested that SEOV plays an important role in human hantavirus infections They also reinforce the need for vigilance in preventing HFRS caused by hantaviruses in the coastal region J. Med. Virol. 82:987 995, 2010. (C) 2010 Wiley-Liss, Inc |
收录类别 | SCI |
资助信息 | Grant sponsor: Chinese Ministry of Science and Technology; Grant numbers: 2002DIB40095, 2003BA712A08-02; Grant spon- sor: Zhejiang Tianyuan Bio-Pharmaceutical Co., Ltd. |
语种 | 英语 |
源URL | [http://159.226.149.26:8080/handle/152453/9611] ![]() |
专题 | 昆明动物研究所_其他 |
作者单位 | 1.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China 2.State Key Laboratory for Infectious Disease Prevention and Control, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China 3.Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province, Chin 4.Cixi Center for Disease Control and Prevention, Cixi, Zhejiang Province, China 5.Ruian Center for Disease Control and Prevention, Ruian, Zhejiang Province, China 6.Ohai District Center for Disease Control and Prevention, Ouhai District, Wenzhou, Zhejiang Province, China 7.Department of Pathology, University of Georgia, Athens, Georgia 8.Department of Virology, Infection Biology Research Program, Haartman Institute, University of Helsinki, Helsinki, Finland |
推荐引用方式 GB/T 7714 | Zhang YZ[*],Lin XD,Guo WP,et al. Hantaviruses in Small Mammals and Humans in the Coastal Region of Zhejiang Province, China[J]. JOURNAL OF MEDICAL VIROLOGY,2010,82(6):987-995. |
APA | Zhang YZ[*].,Lin XD.,Guo WP.,Fan FN.,Huang XM.,...&Liao XW.(2010).Hantaviruses in Small Mammals and Humans in the Coastal Region of Zhejiang Province, China.JOURNAL OF MEDICAL VIROLOGY,82(6),987-995. |
MLA | Zhang YZ[*],et al."Hantaviruses in Small Mammals and Humans in the Coastal Region of Zhejiang Province, China".JOURNAL OF MEDICAL VIROLOGY 82.6(2010):987-995. |
入库方式: OAI收割
来源:昆明动物研究所
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