Long-term exposure to extremely low-frequency magnetic fields impairs spatial recognition memory in mice
文献类型:期刊论文
作者 | Fu Y1,2,3; Wang CK4; Wang JH1,2; Lei YL1,2; Ma YY[*]1,2 |
刊名 | CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
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出版日期 | 2008 |
卷号 | 35期号:7页码:797-800 |
关键词 | electromagnetic field extremely low-frequency mice spatial recognition memory Y-maze |
ISSN号 | 0305-1870 |
通讯作者 | yuanma0716@vip.sina.com |
英文摘要 | 1. In the present study, we investigated the short- and long-term effects of extremely low-frequency (ELF) magnetic fields on spatial recognition memory in mice by using a two-trial recognition Y-maze that is based on the innate tendency of rodents to explore novel environments. 2. Mice were exposed to 25 or 50 Hz electromagnetic fields for either 7 (short term) or 25 days (long term) and then tested in the Y-maze. 3. The results indicated that neither short- nor long-term exposure to magnetic fields affected the locomotor activity of mice in the Y-maze. However, long-term exposure to 50 Hz fields reduced recognition of the novel arm. 4. Our findings suggest that ELF magnetic fields impair spatial recognition memory in the Y-maze depending on the field strength and/or duration of exposure. |
学科主题 | Pharmacology & Pharmacy ; Physiology |
收录类别 | SCI |
资助信息 | This study was supported by National Science Foundation of China (NSFC 30470553, 30530270, 30670669 and 30770700), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810, 2006AA02A116), the Major State Basic Research of China (NO2003CB716600), Chinese–Finnish International Collaboration Project-neuro (30621130076), Program of CASC (KSCX1-YW-R-33, YZ200737), National Key Technologies R&D Program and Yunnan Science and Technique Program (2006PT08-2). |
原文出处 | 200835797.pdf |
语种 | 英语 |
公开日期 | 2010-08-24 |
源URL | [http://159.226.149.42:8088/handle/152453/5469] ![]() |
专题 | 昆明动物研究所_认知障碍病理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 昆明动物研究所_神经系统编码 昆明动物研究所_中国科学院昆明灵长类研究中心 |
作者单位 | 1.Laboratory of Primate Neuroscience Research and Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology 2.Kunming Primate Research Center, Chinese Academy of Sciences, Kunming, Yunnan 3.Graduate University of Chinese Academy of Sciences, Beijin 4.Department of Pharmacology, Medical College, Xiamen University, Xiamen, Fujian, China |
推荐引用方式 GB/T 7714 | Fu Y,Wang CK,Wang JH,et al. Long-term exposure to extremely low-frequency magnetic fields impairs spatial recognition memory in mice[J]. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY,2008,35(7):797-800. |
APA | Fu Y,Wang CK,Wang JH,Lei YL,&Ma YY[*].(2008).Long-term exposure to extremely low-frequency magnetic fields impairs spatial recognition memory in mice.CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY,35(7),797-800. |
MLA | Fu Y,et al."Long-term exposure to extremely low-frequency magnetic fields impairs spatial recognition memory in mice".CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 35.7(2008):797-800. |
入库方式: OAI收割
来源:昆明动物研究所
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