A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta)
文献类型：期刊论文
| 作者 | Wu J1,2; Wang WC1,2; Li L5; Liu L5; Wang GM5; Tan H1,2,4; Jiang HH1,2,4; Wang JH1,2; Ma YY[*]1,2,3; Hu XT[*]1,2,3 |
| 刊名 | JOURNAL OF NEUROSCIENCE METHODS
 |
| 出版日期 | 2010 |
| 卷号 | 193期号:2页码:203-209 |
| 关键词 | Magnetic resonance imaging (MRI) Macaca mulatta Subcortical structure Targeting accuracy |
| 通讯作者 | yuanma0716@vip.sina.com ; xthu@mail.kiz.ac.cn. |
| 合作状况 | 其它 |
| 英文摘要 | The accurate implantation of microelectrodes is a significant difficulty facing many neurophysiologists This paper reports on a new method used to promote the precise positioning of electrode implantation through magnetic resonance imaging (MRI) allowing both the relevant brain structure and the MRI-visible external markers anchored on the skull (In this case rigid glass tubes with a 0 5 mm Internal diameter) to be displayed By referencing these markers the coordinates of the brain target were calculated Using this novel approach recording electrodes were successfully Implanted Into the superior colliculus (SC) of rhesus monkeys with an error <1 mm and its neuronal discharge signals were obtained This new method allows neurophysiologists to precisely target the small deep brain structures of monkeys and study their electrophysiological characteristics in detail |
| 收录类别 | SCI |
| 资助信息 | This study was supported by National Science Foun- dation of China (NSFC 30870825, 30770700 and 31070963), 973 Program (2007CB947703), Program of CASC (KSCX1-YW-R-33 and KSCX2-YW-R-261),WestLightFoundationoftheChineseAcademy of Sciences. |
| 语种 | 英语 |
| 公开日期 | 2010-12-20 |
| 源URL | [http://159.226.149.42:8088/handle/353002/6549]  |
| 专题 | 昆明动物研究所_神经系统编码 昆明动物研究所_认知障碍病理学 |
| 作者单位 | 1.State Key Laboratory of Brain and Cognitive Science, PR China 2.Kunming Institute of Zoology, Chinese Academy of Sciences, Jiaochangdong Road No. 32, Kunming, Yunnan 650223, PR China 3.Institute of Biophysics, Chinese Academy of Sciences, Datun Road No. 15, Beijing 100101, PR China 4.Graduate School of Chinese Academy of Sciences, Beijing, PR China 5.Medical Image Office, Kunming General Hospital of PLA, Yunnan, PR China |
| 推荐引用方式 GB/T 7714 | Wu J,Wang WC,Li L,et al. A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta)[J]. JOURNAL OF NEUROSCIENCE METHODS,2010,193(2):203-209. |
| APA | Wu J.,Wang WC.,Li L.,Liu L.,Wang GM.,...&Hu XT[*].(2010).A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta).JOURNAL OF NEUROSCIENCE METHODS,193(2),203-209. |
| MLA | Wu J,et al."A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta)".JOURNAL OF NEUROSCIENCE METHODS 193.2(2010):203-209. |
入库方式： OAI收割
来源：昆明动物研究所
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