中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
The effect of prenatal morphine exposure on memory consolidation in the chick

文献类型:期刊论文

作者Che Y1,2,3; Sun HY1,2; Ma YY[*]1,2; Tan H1,2; Peng YP1; Zeng T1
刊名NEUROSCIENCE LETTERS
出版日期2005
卷号380期号:3页码:300–304
关键词Morphine Chick Embryo One-trial passive avoidance learning
通讯作者yuanma0716@vip.sina.com
合作状况其它
英文摘要The central nervous system exhibits remarkable plasticity in early life and can be altered significantly by prenatal morphine exposure. Previous studies show that prenatal morphine exposure may alter the capacity for learning and memory in post-partum chicks. The one-trial passive avoidance learning paradigm with 1-day-old chicks is an excellent model to study several mechanisms of memory formation, including STM, ITM, and LTM. The following represents our investigation of the effect of prenatal morphine exposure on learning and memory deficits in the chick. In these experiments, morphine was injected into the airspace of eggs (20 mg/kg) and the one-trial passive avoidance learning paradigm was used to test the effect of prenatal morphine exposure on memory consolidation. The data suggest that chicks injected with morphine daily from E12 to E16 had significantly impaired long-term memory at 120 min after training (p<0.001) but not intermediate-term memory at 30 min after training.
收录类别SCI
资助信息This work was supported by Chinese Academy of Sci- ence Grants (KSCX2-SW for M.Y.), National Basic Re- search Program of China, Chinese National Science Founda- tion (30470553), Program of Chinese Academy of Science (KJCX1-01, KJCX1-09).
语种英语
源URL[http://159.226.149.26:8080/handle/152453/9661]  
专题昆明动物研究所_认知障碍病理学
作者单位1.Kunming Institute of Zoology, Chinese Academy of Science, Kunming 650223, PR China
2.Graduate School of the Chinese Academy of Science, Beijing 100039, PR China
3.School of Life Science, Suzhou University, Suzhou 215006, PR China
推荐引用方式
GB/T 7714
Che Y,Sun HY,Ma YY[*],et al. The effect of prenatal morphine exposure on memory consolidation in the chick[J]. NEUROSCIENCE LETTERS,2005,380(3):300–304.
APA Che Y,Sun HY,Ma YY[*],Tan H,Peng YP,&Zeng T.(2005).The effect of prenatal morphine exposure on memory consolidation in the chick.NEUROSCIENCE LETTERS,380(3),300–304.
MLA Che Y,et al."The effect of prenatal morphine exposure on memory consolidation in the chick".NEUROSCIENCE LETTERS 380.3(2005):300–304.

入库方式: OAI收割

来源:昆明动物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。