The effect of prenatal morphine exposure on memory consolidation in the chick
文献类型:期刊论文
作者 | Che Y1,2,3; Sun HY1,2; Ma YY[*]1,2; Tan H1,2; Peng YP1; Zeng T1 |
刊名 | NEUROSCIENCE LETTERS
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出版日期 | 2005 |
卷号 | 380期号:3页码:300–304 |
关键词 | Morphine Chick Embryo One-trial passive avoidance learning |
通讯作者 | yuanma0716@vip.sina.com |
合作状况 | 其它 |
英文摘要 | The central nervous system exhibits remarkable plasticity in early life and can be altered significantly by prenatal morphine exposure. Previous studies show that prenatal morphine exposure may alter the capacity for learning and memory in post-partum chicks. The one-trial passive avoidance learning paradigm with 1-day-old chicks is an excellent model to study several mechanisms of memory formation, including STM, ITM, and LTM. The following represents our investigation of the effect of prenatal morphine exposure on learning and memory deficits in the chick. In these experiments, morphine was injected into the airspace of eggs (20 mg/kg) and the one-trial passive avoidance learning paradigm was used to test the effect of prenatal morphine exposure on memory consolidation. The data suggest that chicks injected with morphine daily from E12 to E16 had significantly impaired long-term memory at 120 min after training (p<0.001) but not intermediate-term memory at 30 min after training. |
收录类别 | SCI |
资助信息 | This work was supported by Chinese Academy of Sci- ence Grants (KSCX2-SW for M.Y.), National Basic Re- search Program of China, Chinese National Science Founda- tion (30470553), Program of Chinese Academy of Science (KJCX1-01, KJCX1-09). |
语种 | 英语 |
源URL | [http://159.226.149.26:8080/handle/152453/9661] ![]() |
专题 | 昆明动物研究所_认知障碍病理学 |
作者单位 | 1.Kunming Institute of Zoology, Chinese Academy of Science, Kunming 650223, PR China 2.Graduate School of the Chinese Academy of Science, Beijing 100039, PR China 3.School of Life Science, Suzhou University, Suzhou 215006, PR China |
推荐引用方式 GB/T 7714 | Che Y,Sun HY,Ma YY[*],et al. The effect of prenatal morphine exposure on memory consolidation in the chick[J]. NEUROSCIENCE LETTERS,2005,380(3):300–304. |
APA | Che Y,Sun HY,Ma YY[*],Tan H,Peng YP,&Zeng T.(2005).The effect of prenatal morphine exposure on memory consolidation in the chick.NEUROSCIENCE LETTERS,380(3),300–304. |
MLA | Che Y,et al."The effect of prenatal morphine exposure on memory consolidation in the chick".NEUROSCIENCE LETTERS 380.3(2005):300–304. |
入库方式: OAI收割
来源:昆明动物研究所
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