A genomic survey on the immune differences among Sinocyclocheilus fishes
文献类型：期刊论文
| 作者 | Qiu Y1; Yang JX2; Shi Q[*]1,4,5; Jiang WS2; Chen XL3; Bian C1,4 |
| 刊名 | COMMUNICATIVE & INTEGRATIVE BIOLOGY
 |
| 出版日期 | 2016 |
| 卷号 | 9期号:6页码:e1255833 |
| 关键词 | Sinocyclocheilus fishes acquired immune adaptation immunity innate immune |
| 通讯作者 | shiqiong@genomics.cn |
| 英文摘要 | In our previous work, we reported comparative genomics studies on 3 Sinocyclocheilus fishes, including the surface-dwelling S. graham (Sg), the semi-cave-dewlling S. rhinocerous (Sr) and the cave-restricted S. anshuiensis (Sa). Here, we performed a genomic survey on the immunity differences among the 3 fishes by combination of the genome and transcriptome data. Our results demonstrate that immune-related genetic pathways in Sa and Sr present more similarities than Sg. The innate immune activity in Sa seems to be higher than Sg and Sr, while Sr owns more copy numbers of MHC-related genes (related with the acquired immune system) than Sg and Sa. These differential immune activities in the 3 Sinocyclocheilus species may be due to their differential habitats. Generally speaking, most immunity genes transcribe the lowest levels in Sa when compared with Sg and Sr, which may be associate with a less various microbial environment in the cave-restricted habitat. However, Sr has more members of MHC-related genes than those in Sg and Sa, suggesting a great contribution from the semi-cave-dwelling condition. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by China Shenzhen Special Program for Future Industrial Development (No. JSGG20141020113728803), Special Project on the Integration of Industry, Education andResearchofGuangdongProvince(No.2013B090800017),and Zhenjiang Leading Talent Program for Innovation and Entrepreneurship. |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10792]  |
| 专题 | 昆明动物研究所_系统进化与生物地理学 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Shenzhen Academy of Marine Sciences, BGI Fisheries, BGI, Shenzhen, China 2.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 3.BGI-Shenzhen, BGI, Shenzhen, China 4.BGI Research Center for Aquatic Genomics, Chinese Academy of Fishery Sciences, Shenzhen, China 5.Laboratory of Aquatic Genomics, College of Ecology and Evolution, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China |
| 推荐引用方式 GB/T 7714 | Qiu Y,Yang JX,Shi Q[*],et al. A genomic survey on the immune differences among Sinocyclocheilus fishes[J]. COMMUNICATIVE & INTEGRATIVE BIOLOGY,2016,9(6):e1255833. |
| APA | Qiu Y,Yang JX,Shi Q[*],Jiang WS,Chen XL,&Bian C.(2016).A genomic survey on the immune differences among Sinocyclocheilus fishes.COMMUNICATIVE & INTEGRATIVE BIOLOGY,9(6),e1255833. |
| MLA | Qiu Y,et al."A genomic survey on the immune differences among Sinocyclocheilus fishes".COMMUNICATIVE & INTEGRATIVE BIOLOGY 9.6(2016):e1255833. |
入库方式： OAI收割
来源：昆明动物研究所
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