Distribution of vasopressin, oxytocin and vasoactive intestinal polypeptide in the hypothalamus and extrahypothalamic regions of tree shrews
文献类型：期刊论文
| 作者 | Ni RJ1; Shu YM1; Wang J2; Yin JC1; Xu L2; Zhou JN[*]1 |
| 刊名 | NEUROSCIENCE
 |
| 出版日期 | 2014 |
| 卷号 | 265期号:X页码:124-136 |
| 关键词 | hypothalamus paraventricular nucleus suprachiasmatic nucleus amygdala lateral septum |
| 通讯作者 | jnzhou@ustc.edu.cn |
| 合作状况 | 其它 |
| 英文摘要 | Vasopressin (VP), oxytocin (OXT) and vasoactive intestinal polypeptide (VIP) in the brain modulate physiological and behavioral processes in many vertebrates. Day-active tree shrews, the closest relatives of primates, live singly or in pairs in territories that they defend vigorously against intruding conspecifics. However, anatomy concerning peptidergic neuron distribution in the tree shrew brain is less clear. Here, we examined the distribution of VP, OXT and VIP immunoreactivity in the hypothalamus and extrahypothalamic regions of tree shrews (Tupaia belangeri chinensis) using the immunohistochemical techniques. Most of VP and OXT immunoreactive (-ir) neurons were found in the paraventricular nucleus (PVN) and supraoptic nucleus (SON) of the hypothalamus. In addition, VP-ir or OXT-ir neurons were scattered in the preoptic area, anterior hypothalamic areas, dorsomedial hypothalamic nucleus, stria terminalis, bed nucleus of the stria terminalis and medial amygdala. Interestingly, a high density of VP-ir fibers within the ventral lateral septum was observed in males but not in females. Both VP-ir and VIP-ir neurons were found in different subdivisions of the suprachiasmatic nucleus (SCN) with partial overlap. VIP-ir cells and fibers were also scattered in the cerebral cortex, anterior olfactory nucleus, amygdala and dentate gyrus of the hippocampus. These findings provide a comprehensive description of VIP and a detailed mapping of VP and OXT in the hypothalamus and extrahypothalamic regions of tree shrews, which is an anatomical basis for the participation of these neuropeptides in the regulation of circadian behavior and social behavior. |
| 收录类别 | SCI |
| 资助信息 | This research was supported by National Basic Research Program of China (2012CB947602) and Chinese Academy of Sciences (KSCX2-EW-R-12, XDB02030001). |
| 语种 | 英语 |
| WOS记录号 | WOS:000334134400012 |
| 公开日期 | 2014-10-15 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8052]  |
| 专题 | 昆明动物研究所_学习记忆的分子神经机制 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Chinese Academy of Science Key Laboratory of Brain Function and Diseases, School of Life Sciences, University of Science and Technology of China, Hefei 230027, Anhui, PR China 2.Key Laboratory of Animal Models and Human Disease Mechanisms, and Laboratory of Learning and Memory, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, PR China |
| 推荐引用方式 GB/T 7714 | Ni RJ,Shu YM,Wang J,et al. Distribution of vasopressin, oxytocin and vasoactive intestinal polypeptide in the hypothalamus and extrahypothalamic regions of tree shrews[J]. NEUROSCIENCE,2014,265(X):124-136. |
| APA | Ni RJ,Shu YM,Wang J,Yin JC,Xu L,&Zhou JN[*].(2014).Distribution of vasopressin, oxytocin and vasoactive intestinal polypeptide in the hypothalamus and extrahypothalamic regions of tree shrews.NEUROSCIENCE,265(X),124-136. |
| MLA | Ni RJ,et al."Distribution of vasopressin, oxytocin and vasoactive intestinal polypeptide in the hypothalamus and extrahypothalamic regions of tree shrews".NEUROSCIENCE 265.X(2014):124-136. |
入库方式： OAI收割
来源：昆明动物研究所
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