White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia
文献类型：期刊论文
| 作者 | Hao YH1; Liu ZN[*]1; Tan LH2; Kuang F2; Xu L1,4; Yi YH1; Zhang ZS2; Jiang TZ[*]3; Gong GL3; Liu HL1 |
| 刊名 | NEUROREPORT
 |
| 出版日期 | 2006 |
| 卷号 | 17期号:1页码:23-26 |
| 关键词 | diffusion tensor imaging first-episode schizophrenia fractional anisotropy white matter |
| 通讯作者 | zheningl@hotmail.com ; jiangtz@nlpr.ia.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Diffusion tensor imaging studies in schizophrenia have demonstrated lower diffusion anisotropy within white matter that provides information about brain white matter integrity. We have examined whether white matter is abnormal in first-episode schizophrenia by using diffusion tensor imaging. Twenty-one schizophrenic patients and healthy controls underwent diffusion tensor imaging scans that analyzed by using a rigorous voxel-based approach. We found that fractional anisotropy in white matter of the patients was lower than that in controls at the cerebral pecluncle, frontal regions, inferior temporal gyrus, medial parietal lobes, hippocampal gyrus, insula, right anterior cingulum bundle and right corona radiata. These results suggested that white matter integrity of the whole brain was disrupted in early illness onset of schizophrenia. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10589]  |
| 专题 | 昆明动物研究所_学习记忆的分子神经机制 |
| 作者单位 | 1.The Institute of Mental Health,Central South University,Changsha,Hunan, 2.Department of Radiology,Second Xiangya Hospital,CentralSouthUniversity,Changsha,Hunan 3.National Laboratory of Pattern Recognition,Institute of Automation,ChineseA cademy of Sciences,Beijing 4.Laboratory of Learning and Memory,Kunming Institute of Zoology, Chinese Academyof Sciences,Kunming,Y unnan,PRChina |
| 推荐引用方式 GB/T 7714 | Hao YH,Liu ZN[*],Tan LH,et al. White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia[J]. NEUROREPORT,2006,17(1):23-26. |
| APA | Hao YH.,Liu ZN[*].,Tan LH.,Kuang F.,Xu L.,...&Liu HL.(2006).White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia.NEUROREPORT,17(1),23-26. |
| MLA | Hao YH,et al."White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia".NEUROREPORT 17.1(2006):23-26. |
入库方式： OAI收割
来源：昆明动物研究所
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