Tetrahymena Functional Genomics Database (TetraFGD): an integrated resource for Tetrahymena functional genomics
文献类型：期刊论文
| 作者 | Xiong J1; Lu YM1; Feng JM1,2; Yuan DX1; Tian M1,3; Chang Y1,3; Fu CJ1; Wang GY1,3; Zeng HH[*]1; Miao W[*]1 |
| 刊名 | DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
 |
| 出版日期 | 2013 |
| 卷号 | 2013期号:X页码:ID bat008 |
| 通讯作者 | miaowei@ihb.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | The ciliated protozoan Tetrahymena thermophila is a useful unicellular model organism for studies of eukaryotic cellular and molecular biology. Researches on T. thermophila have contributed to a series of remarkable basic biological principles. After the macronuclear genome was sequenced, substantial progress has been made in functional genomics research on T. thermophila, including genome-wide microarray analysis of the T. thermophila life cycle, a T. thermophila gene network analysis based on the microarray data and transcriptome analysis by deep RNA sequencing. To meet the growing demands for the Tetrahymena research community, we integrated these data to provide a public access database: Tetrahymena functional genomics database (TetraFGD). TetraFGD contains three major resources, including the RNA-Seq transcriptome, microarray and gene networks. The RNA-Seq data define gene structures and transcriptome, with special emphasis on exon-intron boundaries; the microarray data describe gene expression of 20 time points during three major stages of the T. thermophila life cycle; the gene network data identify potential gene-gene interactions of 15 049 genes. The TetraFGD provides user-friendly search functions that assist researchers in accessing gene models, transcripts, gene expression data and gene-gene relationships. In conclusion, the TetraFGD is an important functional genomic resource for researchers who focus on the Tetrahymena or other ciliates. |
| 资助信息 | Knowledge Innovation Program of CAS (KSCX2-EW-G-6-4); the Scientific Research Foundation for the Returned Overseas Chinese Scholars State Education Ministry; the open foundation of the State Key Laboratory of Genetics Resources and Evolution (GREKF10-09); National Scientific Data Sharing Platform for population and health, biologic medicine information center of China (2005DKA32402 to W.M.). |
| 语种 | 英语 |
| WOS记录号 | WOS:000316173800001 |
| 公开日期 | 2013-04-11 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7356]  |
| 专题 | 昆明动物研究所_真核细胞进化基因组 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China 2.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 3.University of Chinese Academy of Sciences, Beijing 100049, China |
| 推荐引用方式 GB/T 7714 | Xiong J,Lu YM,Feng JM,et al. Tetrahymena Functional Genomics Database (TetraFGD): an integrated resource for Tetrahymena functional genomics[J]. DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION,2013,2013(X):ID bat008. |
| APA | Xiong J.,Lu YM.,Feng JM.,Yuan DX.,Tian M.,...&Miao W[*].(2013).Tetrahymena Functional Genomics Database (TetraFGD): an integrated resource for Tetrahymena functional genomics.DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION,2013(X),ID bat008. |
| MLA | Xiong J,et al."Tetrahymena Functional Genomics Database (TetraFGD): an integrated resource for Tetrahymena functional genomics".DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION 2013.X(2013):ID bat008. |
入库方式： OAI收割
来源：昆明动物研究所
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