Phylogenetic positions of several amitochondriate protozoa - Evidence from phylogenetic analysis of DNA topoisomerase II
文献类型：期刊论文
| 作者 | He D1,2; Dong JH1,2; Wen JF[*]1; Xin DD1,2; Lu SQ3 |
| 刊名 | SCIENCE IN CHINA SERIES C-LIFE SCIENCES
 |
| 出版日期 | 2005 |
| 卷号 | 48期号:6页码:565-573 |
| 关键词 | protozoa amitochondriate phylogenetic tree DNA topoisomerase II evolutionary position |
| 通讯作者 | wenjf@mail.kiz.ac.cn |
| 英文摘要 | Several groups of parasitic protozoa, as represented by Giardia, Trichomonas, Entamoeba and Microsporida, were once widely considered to be the most primitive extant eukaryotic group - Archezoa. The main evidence for this is their 'lacking mitochondria' and possessing some other primitive features between prokaryotes and eukaryotes, and being basal to all eukaryotes with mitochondria in phylogenies inferred from many molecules. Some authors even proposed that these organisms diverged before the endosymbiotic origin of mitochondria within eukaryotes. This view was once considered to be very significant to the study of origin and evolution of eukaryotic cells (eukaryotes). However, in recent years this has been challenged by accumulating evidence from new studies. Here the sequences of DNA topoisomerase 11 in G lamblia, T vaginalis and E histolytica were identified first by PCR and sequencing, then combining with the sequence data of the microsporidia Encephalitozoon cunicul and other eukaryotic groups of different evolutionary positions from GenBank, phylogenetic trees were constructed by various methods to investigate the evolutionary positions of these amitochondriate protozoa. Our results showed that since the characteristics of DNA topoisomerase 11 make it avoid the defect of 'long-branch attraction' appearing in the previous phylogenetic analyses, our trees can not only reflect effectively the relationship of different major eukaryotic groups, which is widely accepted, but also reveal phylogenetic positions for these amitochondriate protozoa, which is different from the previous phylogenetic trees. They are not the earliest-branching eukaryotes, but diverged after some mitochondriate organisms such as kinetoplastids and mycetozoan; they are not a united group but occupy different phylogenetic positions. Combining with the recent cytological findings of mitochondria-like organelles in them, we think that though some of them (e.g. diplomonads, as represented by Giardia) may occupy a very low evolutionary position, generally these organisms are not as extremely primitive as was thought before; they should be polyphyletic groups diverging after the endosymbiotic origin of mitochondrion to adapt themselves to anaerobic parasitic life. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the Important Di- rection of Knowledge Innovation Program from Chinese Academy of Sciences (Grant No. KSCX2-SW-101C), National Natural Science Foundation of China (Grant Nos. 90408016, 30021004 & 30170135), and Yunnan Province (Grant No. 2000YP19). |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/9655]  |
| 专题 | 昆明动物研究所_真核细胞进化基因组 昆明动物研究所_细胞与分子进化重点实验室 |
| 作者单位 | 1.Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2.Graduate School of the Chinese Academy of Sciences, Beijing 100039, China 3.Capital University of Medical Sciences, Beijing 100054, China |
| 推荐引用方式 GB/T 7714 | He D,Dong JH,Wen JF[*],et al. Phylogenetic positions of several amitochondriate protozoa - Evidence from phylogenetic analysis of DNA topoisomerase II[J]. SCIENCE IN CHINA SERIES C-LIFE SCIENCES,2005,48(6):565-573. |
| APA | He D,Dong JH,Wen JF[*],Xin DD,&Lu SQ.(2005).Phylogenetic positions of several amitochondriate protozoa - Evidence from phylogenetic analysis of DNA topoisomerase II.SCIENCE IN CHINA SERIES C-LIFE SCIENCES,48(6),565-573. |
| MLA | He D,et al."Phylogenetic positions of several amitochondriate protozoa - Evidence from phylogenetic analysis of DNA topoisomerase II".SCIENCE IN CHINA SERIES C-LIFE SCIENCES 48.6(2005):565-573. |
入库方式： OAI收割
来源：昆明动物研究所
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