Evolutionary dynamics of triosephosphate isomerase gene intron location pattern in Metazoa: A new perspective on intron evolution in animals
文献类型：期刊论文
| 作者 | Chen B; Shao JR; Zhuang HF; Wen JF[*] |
| 刊名 | Gene
 |
| 出版日期 | 2017 |
| 卷号 | 602期号:X页码:24-32 |
| 关键词 | Exon-intron arrangement Intron evolution Intron location pattern (ILP) Metazoan divergence Triosephosphate isomerase gene (tim) |
| 通讯作者 | wenjf@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Intron evolution, including its dynamics in the evolutionary transitions and diversification of eukaryotes, remains elusive. Inadequate taxon sampling due to data shortage, unclear phylogenetic framework, and inappropriate outgroup application might be among the causes. Besides, the integrity of all the introns within a gene was often neglected previously. Taking advantage of the ancient conserved triosephosphate isomerase gene (tim), the relatively robust phylogeny of Metazoa, and choanoflagellates as outgroup, the evolutionary dynamics of tim intron location pattern (ILP) in Metazoa was investigated. From 133 representative species of ten phyla, 30 types of ILPs were identified. A most common one, which harbors the maximum six intron positions, is deduced to be the common ancestral tim ILP of Metazoa, which almost had formed in their protozoan ancestor and was surprisingly retained and passed down till to each ancestors of metazoan phyla. In the subsequent animal diversification, it underwent different evolutionary trajectories: within Deuterostomia, it was almost completely retained only with changes in a few species with relatively recently fast-evolving histories, while within the rapidly radiating Protostomia, besides few but remarkable retention, it usually displayed extensive intron losses and a few gains. Therefore, a common ancestral exon-intron arrangement pattern of an animal gene is definitely discovered; besides the 'intron-rich view' of early animal genes being confirmed, the novel insight that high exon-intron re-arrangements of genes seem to be associated with the relatively recently rapid evolution of lineages/species/genomes but have no correlation with the ancient major evolutionary transitions in animal evolution, is revealed. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the National Natural Science Founda- tion of China [grant numbers 31172081, 31401973, 81271869]; the grant from Yunnan Province [grant number 2013FA019], and the open project from State Key Laboratory of Genetic Resources and Evolution [grant number GREKF14-12]. |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10669]  |
| 专题 | 昆明动物研究所_真核细胞进化基因组 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China |
| 推荐引用方式 GB/T 7714 | Chen B,Shao JR,Zhuang HF,et al. Evolutionary dynamics of triosephosphate isomerase gene intron location pattern in Metazoa: A new perspective on intron evolution in animals[J]. Gene,2017,602(X):24-32. |
| APA | Chen B,Shao JR,Zhuang HF,&Wen JF[*].(2017).Evolutionary dynamics of triosephosphate isomerase gene intron location pattern in Metazoa: A new perspective on intron evolution in animals.Gene,602(X),24-32. |
| MLA | Chen B,et al."Evolutionary dynamics of triosephosphate isomerase gene intron location pattern in Metazoa: A new perspective on intron evolution in animals".Gene 602.X(2017):24-32. |
入库方式： OAI收割
来源：昆明动物研究所
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