A call for mtDNA data quality control in forensic science
文献类型：期刊论文
| 作者 | Yao YG1,4; Bravi CM2; Bandelt HJ[*]3 |
| 刊名 | FORENSIC SCIENCE INTERNATIONAL
 |
| 出版日期 | 2004 |
| 卷号 | 141期号:1页码:1-6 |
| 关键词 | mtDNA typing Hypervariable regions Phylogeny Haplogroup Quality control |
| ISSN号 | 0379-0738 |
| 通讯作者 | bandelt@math.uni-hamburg.de |
| 合作状况 | 其它 |
| 英文摘要 | There is increasing evidence that many of the mitochondrial DNA (mtDNA) databases published in the fields of forensic science and molecular anthropology are flawed. An a posteriori phylogenetic analysis of the sequences could help to eliminate most of the errors and thus greatly improve data quality. However, previously published caveats and recommendations along these lines were not yet picked up by all researchers. Here we call for stringent quality control of mtDNA data by haplogroup-directed database comparisons. We take some problematic databases of East Asian mtDNAs, published in the Journal of Forensic Sciences and Forensic Science International, as examples to demonstrate the process of pinpointing obvious errors. Our results show that data sets are not only notoriously plagued by base shifts and artificial recombination but also by lab-specific phantom mutations, especially in the second hypervariable region (HVR-II). |
| 收录类别 | SCI |
| 原文出处 | 20041411.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/5977]  |
| 专题 | 昆明动物研究所_重大疾病机理的遗传学 昆明动物研究所_细胞与分子进化开放实验室 |
| 作者单位 | 1.Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China 2.Centro de Investigaciones en Genetica Basica y Aplicada, School of Veterinary Sciences, National University of La Plata, La Plata, Argentina 3.Fachbereich Mathematik, Universita¨t Hamburg, Bundesstr. 55, 20146 Hamburg, Germany 4.Present address: The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA |
| 推荐引用方式 GB/T 7714 | Yao YG,Bravi CM,Bandelt HJ[*]. A call for mtDNA data quality control in forensic science[J]. FORENSIC SCIENCE INTERNATIONAL,2004,141(1):1-6. |
| APA | Yao YG,Bravi CM,&Bandelt HJ[*].(2004).A call for mtDNA data quality control in forensic science.FORENSIC SCIENCE INTERNATIONAL,141(1),1-6. |
| MLA | Yao YG,et al."A call for mtDNA data quality control in forensic science".FORENSIC SCIENCE INTERNATIONAL 141.1(2004):1-6. |
入库方式： OAI收割
来源：昆明动物研究所
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