Association of FATP1 gene polymorphisms with chicken carcass traits in Chinese meat-type quality chicken populations
文献类型：期刊论文
| 作者 | Wang Y1; Zhu Q1; Zhao XL1; Yao YG[*]2; Liu YP[*]1 |
| 刊名 | MOLECULAR BIOLOGY REPORTS
 |
| 出版日期 | 2010 |
| 卷号 | 37期号:8页码:3683-3690 |
| 关键词 | FATP1 gene Association analysis Carcass traits Chicken SNP |
| 通讯作者 | ygyaozh@gmail.com ; liuyp578@yahoo.com |
| 合作状况 | 其它 |
| 英文摘要 | In this study, we aimed to detect the single nucleotide polymorphisms (SNPs) of the chicken FATP1 gene and discern the potential association between FATP1 SNPs and chicken carcass traits. A total of 620 meat-type quality chickens from six commercial pure lines (S01, S02, S03, S05, S06 and D99) and two cross lines (S05 × S01 and S06 × S01) were screened by using the single-strand conformational polymorphism analysis (SSCP) and DNA sequencing. Five SNPs [g.49360G > A, g.48195G > A, g.46847A > G, g.46818A > G, and g.46555A > G] were identified in chicken FATP1 gene. SNP g.46818 A > G was a rare variant and was not considered in the subsequent analysis. Sixteen haplotypes were reconstructed on the basis of the other four SNPs. The linear regression model analysis indicated that there were significant associations of certain diplotypes with part of carcass traits, such as live weight (LW), carcass weight (CW), and semi-eviscerated weight (SEW) (P < 0.05). In particular, diplotype H2H4 had a negative effect on LW, CW, SEW, and abdominal fat weight (AW); diplotype H6H10 had the highest reducing effect on subcutaneous fat thickness (SFT). Our results suggested that FATP1gene polymorphisms were associated with chicken carcass traits or was linked with the major gene. The SNPs in this gene may be utilized as potential markers for marker-assisted selection (MAS) during chicken breeding. |
| 收录类别 | 其他 |
| 资助信息 | This work was financially supported by the National 863 Project of China (2008AA101001), the Science Fund for Young Scholars in Sichuan Province (ZQ 026-017), and Yunnan Province (2008CD175 and 2009CI119). |
| 语种 | 英语 |
| 公开日期 | 2010-10-28 |
| 源URL | [http://159.226.149.42:8088/handle/152453/6336]  |
| 专题 | 昆明动物研究所_重大疾病机理的遗传学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.College of Animal Science and Technology, Sichuan Agricultural University, Xinkang Road 46#, Ya’an, 625014 Sichuan, People’s Republic of China 2.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, 650223 Kunming, Yunnan, China |
| 推荐引用方式 GB/T 7714 | Wang Y,Zhu Q,Zhao XL,et al. Association of FATP1 gene polymorphisms with chicken carcass traits in Chinese meat-type quality chicken populations[J]. MOLECULAR BIOLOGY REPORTS,2010,37(8):3683-3690. |
| APA | Wang Y,Zhu Q,Zhao XL,Yao YG[*],&Liu YP[*].(2010).Association of FATP1 gene polymorphisms with chicken carcass traits in Chinese meat-type quality chicken populations.MOLECULAR BIOLOGY REPORTS,37(8),3683-3690. |
| MLA | Wang Y,et al."Association of FATP1 gene polymorphisms with chicken carcass traits in Chinese meat-type quality chicken populations".MOLECULAR BIOLOGY REPORTS 37.8(2010):3683-3690. |
入库方式： OAI收割
来源：昆明动物研究所
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