Trends in new leprosy case detection over 57 years (1952-2008) in Yuxi, Yunnan Province of Southwest China
文献类型：期刊论文
| 作者 | Li YY[*]1; Li XA2; He L1; Wang D3,4; Chen WY1; Chen L2; Lu JB2; Yao YG3 |
| 刊名 | LEPROSY REVIEW
 |
| 出版日期 | 2011 |
| 卷号 | 82期号:1页码:6-16 |
| 通讯作者 | yyeli2000@yahoo.com.cn |
| 合作状况 | 其它 |
| 英文摘要 | Background: Leprosy control and management in China was maintained via a vertical system. Despite substantial achievements in leprosy control in the past decades, leprosy has not been completely eliminated in several endemic areas of Yunnan Province, China. Objectives: To report the epidemiological trends and management of leprosy in Yuxi, Yunnan Province from 1952 to 2008. Design: Diagnosis, control, and treatment data for 2223 leprosy cases detected from 1952 to 2008 were analysed. Results: Two large-scale house-to-house surveys were launched in 1957-1958 and 1964-1965, and a remarkable number of new cases were identified during these two surveys. The overall prevalence rate of leprosy in the Yuxi region presented a roughly unimodal distribution between 1952 and 2008, with a peak (9.27 per 10 000 population) in 1965. This reflects a combination of case detection and duration of treatment. Overall, the age distribution of the patients changed dramatically over the years, and there were only two childhood cases between 1995 and 2008 (both occurring in 1998). Nearly half of the total cases (49.1%) were classified as multibacillary leprosy type. With the introduction and ubiquitous coverage of the WHO multi-drug therapy (MDT) in this area, leprosy elimination was achieved in 1992. In recent years, the majority of cases (>80%) were detected by passive approaches, and there is an increasing tendency to find multibacillary leprosy patients. Conclusions: Our results provide an overall profile of our 57-year effort regarding the leprosy control in the Yuxi region. The trend in detection of new cases in recent years suggested that the transmission of leprosy has stopped in the area or, at least, dramatically declined |
| 收录类别 | SCI |
| 资助信息 | We also thank the patients for their participation in this study, the two anonymous reviewers for their critical reading of the early version of the manuscript, and Miss Diana Chen for language editing. X.-A. L. was supported by the Yuxi city (2008-9038). Y.-G. Y. was supported by Yunnan Province (2009CI119), Chinese Academy of Sciences and the National Science Foundation of China (30925021). |
| 语种 | 英语 |
| 公开日期 | 2012-03-16 |
| 源URL | [http://159.226.149.42:8088/handle/353002/6868]  |
| 专题 | 昆明动物研究所_重大疾病机理的遗传学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Department of Dermatology, the First Affiliated Hospital of Kunming Medical College, Kunming, Yunnan, 650032, China 2.Yuxi City Center for Disease Control and Prevention, Yuxi, Yunnan, 653100, China 3.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, 650223, China 4.Graduate School of the Chinese Academy of Sciences, Beijing 100039, China |
| 推荐引用方式 GB/T 7714 | Li YY[*],Li XA,He L,et al. Trends in new leprosy case detection over 57 years (1952-2008) in Yuxi, Yunnan Province of Southwest China[J]. LEPROSY REVIEW,2011,82(1):6-16. |
| APA | Li YY[*].,Li XA.,He L.,Wang D.,Chen WY.,...&Yao YG.(2011).Trends in new leprosy case detection over 57 years (1952-2008) in Yuxi, Yunnan Province of Southwest China.LEPROSY REVIEW,82(1),6-16. |
| MLA | Li YY[*],et al."Trends in new leprosy case detection over 57 years (1952-2008) in Yuxi, Yunnan Province of Southwest China".LEPROSY REVIEW 82.1(2011):6-16. |
入库方式： OAI收割
来源：昆明动物研究所
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