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An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination

文献类型:期刊论文

作者Fan L1,2; Yao YG[*]1
刊名MITOCHONDRION
出版日期2013
卷号13期号:4页码:360-363
关键词mtDNA Haplogroup Determination Scoring system
通讯作者mitotool@gmail.com ; ygyaozh@gmail.com
合作状况其它
英文摘要The determination of human mitochondrial DNA (mtDNA) haplogroups is not only crucial in anthropological and forensic studies, but is also helpful in the medical field to prevent establishment of wrong disease associations. In recent years, high-throughput technologies and the huge amounts of data they create, as well as the regular updates to the mtDNA phylogenetic tree, mean that there is a need for an automated approach which can make a speedier determination of haplogroups than can be made by using the traditional manual method. Here, we update the MitoTool (www.mitotool.org) by incorporating a novel scoring system for the determination of mtDNA into haplogroups, which has advantages on speed, accuracy and ease of implementation. In order to make the access to MitoTool easier, we also provide a stand-alone version of the program that will run on a local computer and this version is freely available at the MitoTool website. (C) 2013 Elsevier B.V. and Mitochondria Research Society.
收录类别SCI
资助信息This work was supported by the National Science Foundation of China (30925021), the Top Talents Program of Yunnan Province (2009CI119) and the Chinese Academy of Sciences.
语种英语
WOS记录号WOS:000320294600014
公开日期2013-09-24
源URL[http://159.226.149.42:8088/handle/152453/7673]  
专题昆明动物研究所_重大疾病机理的遗传学
昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位1.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China.
2.School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, China
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GB/T 7714
Fan L,Yao YG[*]. An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination[J]. MITOCHONDRION,2013,13(4):360-363.
APA Fan L,&Yao YG[*].(2013).An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination.MITOCHONDRION,13(4),360-363.
MLA Fan L,et al."An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination".MITOCHONDRION 13.4(2013):360-363.

入库方式: OAI收割

来源:昆明动物研究所

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