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An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination
文献类型：期刊论文
| 作者 | Fan L1,2; Yao YG[*]1 |
| 刊名 | MITOCHONDRION
 |
| 出版日期 | 2013 |
| 卷号 | 13期号:4页码:360-363 |
| 关键词 | mtDNA Haplogroup Determination Scoring system |
| 通讯作者 | mitotool@gmail.com ; ygyaozh@gmail.com |
| 合作状况 | 其它 |
| 英文摘要 | The determination of human mitochondrial DNA (mtDNA) haplogroups is not only crucial in anthropological and forensic studies, but is also helpful in the medical field to prevent establishment of wrong disease associations. In recent years, high-throughput technologies and the huge amounts of data they create, as well as the regular updates to the mtDNA phylogenetic tree, mean that there is a need for an automated approach which can make a speedier determination of haplogroups than can be made by using the traditional manual method. Here, we update the MitoTool (www.mitotool.org) by incorporating a novel scoring system for the determination of mtDNA into haplogroups, which has advantages on speed, accuracy and ease of implementation. In order to make the access to MitoTool easier, we also provide a stand-alone version of the program that will run on a local computer and this version is freely available at the MitoTool website. (C) 2013 Elsevier B.V. and Mitochondria Research Society. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the National Science Foundation of China (30925021), the Top Talents Program of Yunnan Province (2009CI119) and the Chinese Academy of Sciences. |
| 语种 | 英语 |
| WOS记录号 | WOS:000320294600014 |
| 公开日期 | 2013-09-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7673]  |
| 专题 | 昆明动物研究所_重大疾病机理的遗传学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China. 2.School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, China |
| 推荐引用方式 GB/T 7714 | Fan L,Yao YG[*]. An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination[J]. MITOCHONDRION,2013,13(4):360-363. |
| APA | Fan L,&Yao YG[*].(2013).An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination.MITOCHONDRION,13(4),360-363. |
| MLA | Fan L,et al."An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination".MITOCHONDRION 13.4(2013):360-363. |
入库方式： OAI收割
来源：昆明动物研究所
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