No association between genetic polymorphisms of the NDUFS7 gene and schizophrenia in Han Chinese
文献类型：期刊论文
| 作者 | Ma L1,3; Zhang W1,3; Tang JS2; Tan LW2; Yao YG[*]1; Chen XG2 |
| 刊名 | PSYCHIATRIC GENETICS
 |
| 出版日期 | 2013 |
| 卷号 | 23期号:1页码:29–32 |
| 关键词 | Han Chinese NDUFS7 schizophrenia tagging single-nucleotide polymorphism |
| 通讯作者 | ygyaozh@gmail.com |
| 合作状况 | 其它 |
| 英文摘要 | Accumulating evidence suggests that mitochondrial dysfunction contributes toward the pathogenesis of psychiatric diseases. NADH dehydrogenase Fe-S protein 7 (NDUFS7), a subunit of respiratory chain complex I, has been reported recently to be associated with bipolar disorder. To test whether this gene can confer a wide variety of psychiatric disorders, we carried out a case-control association analysis of three tagging single-nucleotide polymorphisms (rs2074896, rs2074897, and rs2074898) in the NDUFS7 gene by sequencing 330 Han Chinese patients with schizophrenia and 330 well-matched healthy controls. We found no significant difference in the frequency distributions of alleles, genotypes, and haplotypes between the cases and the controls, indicating no active role of this gene in schizophrenia. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the National Natural Science Foundation of China (30900486, 31000557) and Yunnan Province (2009CI119). |
| 语种 | 英语 |
| WOS记录号 | WOS:000312530000004 |
| 公开日期 | 2013-12-17 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7739]  |
| 专题 | 昆明动物研究所_重大疾病机理的遗传学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 2.Institute of Mental Health the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China 3.Graduate University of the Chinese Academy of Sciences, Beijing, China |
| 推荐引用方式 GB/T 7714 | Ma L,Zhang W,Tang JS,et al. No association between genetic polymorphisms of the NDUFS7 gene and schizophrenia in Han Chinese[J]. PSYCHIATRIC GENETICS,2013,23(1):29–32. |
| APA | Ma L,Zhang W,Tang JS,Tan LW,Yao YG[*],&Chen XG.(2013).No association between genetic polymorphisms of the NDUFS7 gene and schizophrenia in Han Chinese.PSYCHIATRIC GENETICS,23(1),29–32. |
| MLA | Ma L,et al."No association between genetic polymorphisms of the NDUFS7 gene and schizophrenia in Han Chinese".PSYCHIATRIC GENETICS 23.1(2013):29–32. |
入库方式： OAI收割
来源：昆明动物研究所
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