MitoTool: A web server for the analysis and retrieval of human mitochondrial DNA sequence variations
文献类型：期刊论文
| 作者 | Fan L1,2; Yao YG[*]1 |
| 刊名 | MITOCHONDRION
 |
| 出版日期 | 2011 |
| 卷号 | 11期号:2页码:351-356 |
| 关键词 | mtDNA Haplogroup Database Statistics |
| 通讯作者 | mitotool@gmail.com ; ygyaozh@gmail.com |
| 合作状况 | 其它 |
| 英文摘要 | MitoTool, a web-based bioinformatics platform, is designed for deciphering human mitochondrial DNA (mtDNA) data in batch mode. The platform has advantages in (i) parsing diverse types of mtDNA data; (ii) automatically classifying haplogroup according to mtDNA sequences or variants; (iii) discovering possibly missing variants of the samples with claimed haplogroups status; (iv) estimating the evolutionary conservation index, protein coding effect and potential pathogenicity of certain substitutions; (v) performing statistical analysis for haplogroup distribution frequency between case and control groups. Furthermore, it offers an integrated database for retrieving five types of mitochondrion-related information. The MitoTool is freely accessed at http://www.mitotool.org. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the National Science Foundation of China (30925021), Yunnan Province (云南省高端人才计 划2009CI119) and the Chinese Academy of Sciences. |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/9599]  |
| 专题 | 昆明动物研究所_重大疾病机理的遗传学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China 2.Graduate School of the Chinese Academy of Sciences, Beijing 100039, China |
| 推荐引用方式 GB/T 7714 | Fan L,Yao YG[*]. MitoTool: A web server for the analysis and retrieval of human mitochondrial DNA sequence variations[J]. MITOCHONDRION,2011,11(2):351-356. |
| APA | Fan L,&Yao YG[*].(2011).MitoTool: A web server for the analysis and retrieval of human mitochondrial DNA sequence variations.MITOCHONDRION,11(2),351-356. |
| MLA | Fan L,et al."MitoTool: A web server for the analysis and retrieval of human mitochondrial DNA sequence variations".MITOCHONDRION 11.2(2011):351-356. |
入库方式： OAI收割
来源：昆明动物研究所
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