Age-related expression profile of the SLC27A1 gene in chicken tissues
文献类型：期刊论文
| 作者 | Wang Y1; Zhu Q1; Zhao XL1; Yao YG2; Liu YP[*]1 |
| 刊名 | MOLECULAR BIOLOGY REPORTS
 |
| 出版日期 | 2011 |
| 卷号 | 38期号:8页码:5139-5145 |
| 关键词 | Chicken Real-time PCR SLC27A1 Age Breed Tissue |
| 通讯作者 | liuyp578@yahoo.com |
| 合作状况 | 其它 |
| 英文摘要 | The solute carrier family 27 (SLC27, also known as fatty acid transport proteins [FATPs]) plays important biological roles in cells. However, there is no report about the expression profile of SLC27 member in chicken. In this study, we quantified the expression of SLC27A1 (FATP1) mRNA in a mountainous black-boned chicken breed (MB) and a commercial meat type chicken breed (S01), to discern the tissue and age-related specific expression pattern and their potential involvement in fat deposition and muscle fatty acid metabolism. Real-time quantitative PCR assays were developed for accurate measurement of SLC27A1 mRNA levels in different tissues from chicken with different ages (0-12 weeks). Expression of SLC27A1 mRNA was detected in all tissues examined. There was a significantly age-related change of the SLC27A1 mRNAs in heart, breast muscle (BMW), leg muscle (LMW), liver, and abdominal fat (AF) tissues (P < 0.05). The breast muscle and leg muscle tissues had the highest expression of SLC27A1 mRNA than the other tissues from the same individual at 0, 2 and 4 weeks. The overall SLC27A1 mRNA level exhibited a "rise-decline" developmental change in all tissues except for breast muscle, subcutaneous fat, and brain. The S01 chicken had a higher expression of the SLC27A1 mRNA in breast muscle, subcutaneous fat, and heart tissues than the MB chicken. Our results showed that the expression of SLC27A1 mRNA in chicken tissues exhibits specific developmental changes and age-related patterns. |
| 收录类别 | SCI |
| 资助信息 | This study was supported by the Ministry of Agriculture of China (No. 2009ZX08009-159B), the Program for New Century Excellent Tal- ents in University (NCET-10-0889), the Science Fund for Young Scholars in Sichuan Province (ZQ 026-017), and Yunnan Province (2009CI119). |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10407]  |
| 专题 | 昆明动物研究所_重大疾病机理的遗传学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.College of Animal Science and Technology, Sichuan Agricultural University, Ya’an, Sichuan 625014, China 2.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China |
| 推荐引用方式 GB/T 7714 | Wang Y,Zhu Q,Zhao XL,et al. Age-related expression profile of the SLC27A1 gene in chicken tissues[J]. MOLECULAR BIOLOGY REPORTS,2011,38(8):5139-5145. |
| APA | Wang Y,Zhu Q,Zhao XL,Yao YG,&Liu YP[*].(2011).Age-related expression profile of the SLC27A1 gene in chicken tissues.MOLECULAR BIOLOGY REPORTS,38(8),5139-5145. |
| MLA | Wang Y,et al."Age-related expression profile of the SLC27A1 gene in chicken tissues".MOLECULAR BIOLOGY REPORTS 38.8(2011):5139-5145. |
入库方式： OAI收割
来源：昆明动物研究所
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