Resonance assignments of a VapC family toxin from Clostridium thermocellum
文献类型:期刊论文
作者 | Wang, Chen1,2,3; Xuan, Jinsong1; Cui, Qiu2,3![]() ![]() |
刊名 | BIOMOLECULAR NMR ASSIGNMENTS
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出版日期 | 2016-10-01 |
卷号 | 10期号:2页码:367-371 |
关键词 | VapBC toxin-antitoxin Clostridium thermocellum NMR Chemical shift assignment |
英文摘要 | Toxin-antitoxin (TA) systems widely exist in bacterial plasmids, phages, and chromosomes and play important roles in growth persistence and host-pathogen interaction. Virulence associated protein BC (VapBC) family TAs are the most abundant TAs in bacteria and many pathogens contain a large number of vapBC loci in the genome which have been extensively studied. Clostridium thermocellum, a cellulolytic anaerobic gram-positive bacterium with promising applications in biofuel production, also contains a VapBC TA in the genome. Despite the structures of several VapBC family TAs have been determined, the toxin and anti-toxin components of C. thermocellum VapBC have very low sequence identity to the proteins in PDB. Therefore, the structure and functional mechanism of this TA is largely unknown. Here we reported the NMR resonance assignments of the VapC toxin from C. thermocellum as a basis for further structural and functional studies. |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
类目[WOS] | Biophysics ; Spectroscopy |
研究领域[WOS] | Biophysics ; Spectroscopy |
关键词[WOS] | ANTITOXIN SYSTEMS ; CRYSTAL-STRUCTURE ; MYCOBACTERIUM-TUBERCULOSIS ; REVEALS ; COMPLEX ; PERSISTENCE ; BACTERIA ; LOCI ; ION |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000388287400026 |
源URL | [http://ir.qibebt.ac.cn/handle/337004/9103] ![]() |
专题 | 青岛生物能源与过程研究所_代谢物组学团队 |
作者单位 | 1.Univ Sci & Technol Beijing, Sch Chem & Biol Engn, Dept Biol Sci & Engn, 30 Xueyuan Rd, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, 189 Songling Rd, Qingdao 266101, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, 189 Songling Rd, Qingdao 266101, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Chen,Xuan, Jinsong,Cui, Qiu,et al. Resonance assignments of a VapC family toxin from Clostridium thermocellum[J]. BIOMOLECULAR NMR ASSIGNMENTS,2016,10(2):367-371. |
APA | Wang, Chen,Xuan, Jinsong,Cui, Qiu,&Feng, Yingang.(2016).Resonance assignments of a VapC family toxin from Clostridium thermocellum.BIOMOLECULAR NMR ASSIGNMENTS,10(2),367-371. |
MLA | Wang, Chen,et al."Resonance assignments of a VapC family toxin from Clostridium thermocellum".BIOMOLECULAR NMR ASSIGNMENTS 10.2(2016):367-371. |
入库方式: OAI收割
来源:青岛生物能源与过程研究所
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