中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Resonance assignments of a VapC family toxin from Clostridium thermocellum

文献类型:期刊论文

作者Wang, Chen1,2,3; Xuan, Jinsong1; Cui, Qiu2,3; Feng, Yingang2,3
刊名BIOMOLECULAR NMR ASSIGNMENTS
出版日期2016-10-01
卷号10期号:2页码:367-371
关键词VapBC toxin-antitoxin Clostridium thermocellum NMR Chemical shift assignment
英文摘要Toxin-antitoxin (TA) systems widely exist in bacterial plasmids, phages, and chromosomes and play important roles in growth persistence and host-pathogen interaction. Virulence associated protein BC (VapBC) family TAs are the most abundant TAs in bacteria and many pathogens contain a large number of vapBC loci in the genome which have been extensively studied. Clostridium thermocellum, a cellulolytic anaerobic gram-positive bacterium with promising applications in biofuel production, also contains a VapBC TA in the genome. Despite the structures of several VapBC family TAs have been determined, the toxin and anti-toxin components of C. thermocellum VapBC have very low sequence identity to the proteins in PDB. Therefore, the structure and functional mechanism of this TA is largely unknown. Here we reported the NMR resonance assignments of the VapC toxin from C. thermocellum as a basis for further structural and functional studies.
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Technology
类目[WOS]Biophysics ; Spectroscopy
研究领域[WOS]Biophysics ; Spectroscopy
关键词[WOS]ANTITOXIN SYSTEMS ; CRYSTAL-STRUCTURE ; MYCOBACTERIUM-TUBERCULOSIS ; REVEALS ; COMPLEX ; PERSISTENCE ; BACTERIA ; LOCI ; ION
收录类别SCI
语种英语
WOS记录号WOS:000388287400026
源URL[http://ir.qibebt.ac.cn/handle/337004/9103]  
专题青岛生物能源与过程研究所_代谢物组学团队
作者单位1.Univ Sci & Technol Beijing, Sch Chem & Biol Engn, Dept Biol Sci & Engn, 30 Xueyuan Rd, Beijing 100083, Peoples R China
2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, 189 Songling Rd, Qingdao 266101, Peoples R China
3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, 189 Songling Rd, Qingdao 266101, Peoples R China
推荐引用方式
GB/T 7714
Wang, Chen,Xuan, Jinsong,Cui, Qiu,et al. Resonance assignments of a VapC family toxin from Clostridium thermocellum[J]. BIOMOLECULAR NMR ASSIGNMENTS,2016,10(2):367-371.
APA Wang, Chen,Xuan, Jinsong,Cui, Qiu,&Feng, Yingang.(2016).Resonance assignments of a VapC family toxin from Clostridium thermocellum.BIOMOLECULAR NMR ASSIGNMENTS,10(2),367-371.
MLA Wang, Chen,et al."Resonance assignments of a VapC family toxin from Clostridium thermocellum".BIOMOLECULAR NMR ASSIGNMENTS 10.2(2016):367-371.

入库方式: OAI收割

来源:青岛生物能源与过程研究所

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