Micro/Nanoparticle-Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation
文献类型：期刊论文
| 作者 | Qian, Xiaoqin1; Zheng, Yuanyi2,3; Chen, Yu4 |
| 刊名 | ADVANCED MATERIALS
 |
| 出版日期 | 2016-10-05 |
| 卷号 | 28期号:37页码:8097-8129 |
| 关键词 | cancer therapy micro nanoparticles nanotechnology nanomedicine sonodynamic therapy |
| 英文摘要 | The fast development of photoactivation for cancer treatment provides an efficient photo-therapeutic strategy for cancer treatment, but traditional photodynamic or photothermal therapy suffers from the critical issue of low in vivo penetration depth of tissues. As a non-invasive therapeutic modality, sonodynamic therapy (SDT) can break the depth barrier of photoactivation because ultrasound has an intrinsically high tissue-penetration performance. Micro/nanoparticles can efficiently augment the SDT efficiency based on nanobiotechnology. The state-of-art of the representative achievements on micro/nanoparticle-enhanced SDT is summarized, and specific functions of micro/nanoparticles for SDT are discussed, from the different viewpoints of ultrasound medicine, material science and nanobiotechnology. Emphasis is put on the relationship of structure/composition-SDT performance of micro/nanoparticle-based sonosensitizers. Three types of micro/nanoparticle-augmented SDT are discussed, including organic and inorganic sonosensitizers and micro/nanoparticle-based but sonosensitizer-free strategies to enhance the SDT outcome. SDT-based synergistic cancer therapy augmented by micro/nanoparticles and their biosafety are also included. Some urgent critical issues and potential developments of micro/nanoparticle-augmented SDT for efficient cancer treatment are addressed. It is highly expected that micro/nanoparticle-augmented SDT will be quickly developed as a new and efficient therapeutic modality which will find practical applications in cancer treatment. At the same time, fundamental disciplines regarding materials science, chemistry, medicine and nanotechnology will be advanced. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 关键词[WOS] | INTENSITY FOCUSED ULTRASOUND ; MESOPOROUS SILICA NANOPARTICLES ; GALLIUM-PORPHYRIN COMPLEX ; STIMULI-RESPONSIVE NANOCARRIERS ; EFFICIENT PHOTOTHERMAL THERAPY ; EFFECTIVE PHOTODYNAMIC THERAPY ; SYNERGISTIC HIFU ABLATION ; ANTICANCER DRUG-DELIVERY ; BRAIN-BARRIER DISRUPTION ; INDUCED MAMMARY-TUMOR |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000386103600002 |
| 源URL | [http://ir.sic.ac.cn/handle/331005/22069]  |
| 专题 | 上海硅酸盐研究所_高性能陶瓷和超微结构国家重点实验室_期刊论文 |
| 作者单位 | 1.Jiangsu Univ, Dept Ultrasound, Affiliated Peoples Hosp, Zhenjiang 212002, Jiangsu, Peoples R China 2.Shanghai Jiao Tong Univ, Affiliated Hosp 6, Shanghai 200233, Peoples R China 3.Shanghai Inst Ultrasound Med, Shanghai 200233, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qian, Xiaoqin,Zheng, Yuanyi,Chen, Yu. Micro/Nanoparticle-Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation[J]. ADVANCED MATERIALS,2016,28(37):8097-8129. |
| APA | Qian, Xiaoqin,Zheng, Yuanyi,&Chen, Yu.(2016).Micro/Nanoparticle-Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation.ADVANCED MATERIALS,28(37),8097-8129. |
| MLA | Qian, Xiaoqin,et al."Micro/Nanoparticle-Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation".ADVANCED MATERIALS 28.37(2016):8097-8129. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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