Plasma-Sprayed Titanium Patterns for Enhancing Early Cell Responses
文献类型：期刊论文
| 作者 | Shi, Yunqi1; Xie, Youtao1; Pan, Houhua1; Zheng, Xuebin1; Huang, Liping1; Ji, Fang2; Li, Kai1 |
| 刊名 | JOURNAL OF THERMAL SPRAY TECHNOLOGY
 |
| 出版日期 | 2016-06-01 |
| 卷号 | 25期号:5页码:946-958 |
| 关键词 | MC3T3-E1 cells micro-pattern responses titanium coating |
| 英文摘要 | Titanium coating has been widely used as a biocompatible metal in biomedical applications. However, the early cell responses and long-term fixation of titanium implants are not satisfied. To obviate these defects, in this paper, micro-post arrays with various widths (150-1000 mu m) and intervals (100-300 mu m) were fabricated on the titanium substrate by template-assisted plasma spraying technology. In vitro cell culture experiments showed that MC3T3-E1 cells exhibited significantly higher osteogenic differentiation as well as slightly improved adhesion and proliferation on the micro-patterned coatings compared with the traditional one. The cell number on the pattern with 1000 mu m width reached 130% after 6 days of incubation, and the expressions of osteopontin (OPN) as well as osteocalcin (OC) were doubled. No obvious difference was found in cell adhesion on various size patterns. The present micro-patterned coatings proposed a new modification method for the traditional plasma spraying technology to enhance the early cell responses and convenience for the bone in-growth. |
| WOS标题词 | Science & Technology ; Technology |
| 类目[WOS] | Materials Science, Coatings & Films |
| 研究领域[WOS] | Materials Science |
| 关键词[WOS] | OSTEOBLAST-LIKE CELLS ; SURFACE-ROUGHNESS ; SUBSTRATE MICROTOPOGRAPHY ; EXTRACELLULAR-MATRIX ; PROTEIN ADSORPTION ; FOCAL ADHESION ; OSSEOINTEGRATION ; PROLIFERATION ; DIFFERENTIATION ; IMPLANTS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000381209300007 |
| 源URL | [http://ir.sic.ac.cn/handle/331005/22120]  |
| 专题 | 上海硅酸盐研究所_特种无机涂层重点实验室_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, Key Lab Inorgan Coating Mat, Shanghai 200050, Peoples R China 2.Changhai Hosp, Dept Trauma Orthopaed, Shanghai 200433, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shi, Yunqi,Xie, Youtao,Pan, Houhua,et al. Plasma-Sprayed Titanium Patterns for Enhancing Early Cell Responses[J]. JOURNAL OF THERMAL SPRAY TECHNOLOGY,2016,25(5):946-958. |
| APA | Shi, Yunqi.,Xie, Youtao.,Pan, Houhua.,Zheng, Xuebin.,Huang, Liping.,...&Li, Kai.(2016).Plasma-Sprayed Titanium Patterns for Enhancing Early Cell Responses.JOURNAL OF THERMAL SPRAY TECHNOLOGY,25(5),946-958. |
| MLA | Shi, Yunqi,et al."Plasma-Sprayed Titanium Patterns for Enhancing Early Cell Responses".JOURNAL OF THERMAL SPRAY TECHNOLOGY 25.5(2016):946-958. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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