Prediction of infarct core and salvageable ischemic tissue volumes by analyzing apparent diffusion coefficient without intravenous contrast material
文献类型:期刊论文
作者 | Li Ma; Peiyi Gao; Qingmao Hu; Yan Lin; Lina Jing; Jing Xue; Xiaochun Wang; Zhijun Chen; Yilong Wang; Xiaoling Liao |
刊名 | ACADEMIC RADIOLOGY |
出版日期 | 2010 |
卷号 | 17期号:12页码:1506-1517 |
英文摘要 | Rationale and Objectives: To investigate whether baseline apparent diffusion coefficient (ADC) maps can be employed to predict both infarct core and salvageable ischemic tissue volumes in acute ischemic stroke.Materials and Methods: An automated image analysis system based on baseline ADC maps was tested against 30 patients with acute ischemic stroke of anterior circulation to predict both infarct core and salvageable ischemic tissue volumes. The predicted infarct core and predicted salvageable ischemic tissue were quantitatively and qualitatively compared with follow-up imaging data in recanalization and no recanalization groups, respectively. Direct comparisons with perfusion- and diffusion-weighted magnetic resonance imaging measures were also made. Wilcoxon signed-rank test, Spearman rank correlation, and Bland-Altman plots were performed. Results: In the recanalization group, the predicted infarct core volume was significantly correlated with the final infarct volume (r = 0.868, P < .001). In the no recanalization group, the predicted final infarct volume (sum of the predicted infarct core and salvageable ischemic tissue volumes), as well as the predicted salvageable ischemic tissue volume, was also significantly correlated with the true final infarct volume (r = 0.955, P < .001) and infarct growth (r = 0.918, P < .001), respectively. The volumes of perfusion-diffusion mismatch were significantly larger than those of infarct growth and predicted salvageable ischemic tissue. Good agreement between predicted and true final infarct lesions was visualized by Bland-Altman plots in two groups. Direct visual comparative analysis revealed good qualitative agreement between the true final infarct and predicted lesions in 21 patientsd. |
收录类别 | SCI |
原文出处 | http://www.sciencedirect.com/science/article/pii/S107663321000423X |
语种 | 英语 |
源URL | [http://ir.siat.ac.cn:8080/handle/172644/2715] |
专题 | 深圳先进技术研究院_集成所 |
作者单位 | ACADEMIC RADIOLOGY |
推荐引用方式 GB/T 7714 | Li Ma,Peiyi Gao,Qingmao Hu,et al. Prediction of infarct core and salvageable ischemic tissue volumes by analyzing apparent diffusion coefficient without intravenous contrast material[J]. ACADEMIC RADIOLOGY,2010,17(12):1506-1517. |
APA | Li Ma.,Peiyi Gao.,Qingmao Hu.,Yan Lin.,Lina Jing.,...&Weijian Chen.(2010).Prediction of infarct core and salvageable ischemic tissue volumes by analyzing apparent diffusion coefficient without intravenous contrast material.ACADEMIC RADIOLOGY,17(12),1506-1517. |
MLA | Li Ma,et al."Prediction of infarct core and salvageable ischemic tissue volumes by analyzing apparent diffusion coefficient without intravenous contrast material".ACADEMIC RADIOLOGY 17.12(2010):1506-1517. |
入库方式: OAI收割
来源:深圳先进技术研究院
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