Complement activity of polysaccharides from three different plant parts of Terminalia macroptera extracted as healers do
文献类型：期刊论文
| 作者 | Yuan-Feng Zou; Bing-Zhao Zhang; Kari Tvete Inngjerdingen; Hilde Barsett; Drissa Dialloc; Terje Einar Michaelsen; Berit Smestad Paulsena |
| 刊名 | JOURNAL OF ETHNOPHARMACOLOGY
 |
| 出版日期 | 2014 |
| 英文摘要 | Ethnopharmacological relevance: Water decoctions of the root bark, stem bark and leaves of Terminalia macroptera are used by traditional healers in Mali to cure a wide range of illnesses, such as wounds, hepatitis, malaria, fever, cough and diarrhea as well as tuberculosis. Plant polysaccharides isolated from crude water extracts have previously shown effects related to the immune system. The aims of this study are comparing the properties of the polysaccharides among different plant parts, as well as relationship between chemical characteristics and complement fixation activities when the plant material has been extracted as the traditional healers do, with boiling water directly. Materials and methods: Root bark, stem bark and leaves of Terminalia macroptera were extracted by boiling water, and five purified polysaccharide fractions were obtained by anion exchange chromatography and gel filtration. Chemical compositions were determined by GC of the TMS derivatives of the methyl-glycosides and the linkage determined after permethylation and GC-MS of the derived partly methylated alditol acetates. The bioactivity was determined by the complement fixation assay of the crude extracts and purified fractions. Results: The acidic fraction TRBD-I-I isolated from the root bark was the most active of the fractions isolated. Structural studies showed that all purified fractions are of pectic nature, containing rhamnogalacturonan type I backbone. Arabinogalactan type II side chains were present in all fractions except TRBD-I-II. The observed differences in complement fixation activities among the five purified polysaccharide fractions are probably due to differences in monosaccharide compositions, linkage types and molecular sizes. Conclusion: The crude extracts from root bark and stem bark have similar total activities, both higher than those from leaves. The root bark, leaves and stem bark are all good sources for fractions containing bioactive polysaccharides. But due to sustainability, it is prefer to use leaves rather than the other two plant parts, and then the dosage by weight must be higher when using leaves. |
| 收录类别 | SCI |
| 原文出处 | http://www.sciencedirect.com/science/article/pii/S0378874114004656 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/6277]  |
| 专题 | 深圳先进技术研究院_南沙所 |
| 作者单位 | JOURNAL OF ETHNOPHARMACOLOGY |
| 推荐引用方式 GB/T 7714 | Yuan-Feng Zou,Bing-Zhao Zhang,Kari Tvete Inngjerdingen,et al. Complement activity of polysaccharides from three different plant parts of Terminalia macroptera extracted as healers do[J]. JOURNAL OF ETHNOPHARMACOLOGY,2014. |
| APA | Yuan-Feng Zou.,Bing-Zhao Zhang.,Kari Tvete Inngjerdingen.,Hilde Barsett.,Drissa Dialloc.,...&Berit Smestad Paulsena.(2014).Complement activity of polysaccharides from three different plant parts of Terminalia macroptera extracted as healers do.JOURNAL OF ETHNOPHARMACOLOGY. |
| MLA | Yuan-Feng Zou,et al."Complement activity of polysaccharides from three different plant parts of Terminalia macroptera extracted as healers do".JOURNAL OF ETHNOPHARMACOLOGY (2014). |
入库方式： OAI收割
来源：深圳先进技术研究院
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