MiR-218 mediates tumorigenesis and metastasis: Perspectives and implications
文献类型：期刊论文
| 作者 | Lu YF; Zhang L; Waye MM; Fu WM; Zhang JF. |
| 刊名 | EXPERIMENTAL CELL RESEARCH
 |
| 出版日期 | 2015 |
| 英文摘要 | MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. As a highly conserved miRNA across a variety of species, microRNA-218 (miR-218) was found to play pivotal roles in tumorigenesis and progression. A group of evidence has demonstrated that miR-218 acts as a tumor suppressor by targeting many oncogenes related to proliferation, apoptosis and invasion. In this review, we provide a complex overview of miR-218, including its regulatory mechanisms, known functions in cancer and future challenges as a potential therapeutic target in human cancers. |
| 收录类别 | SCI |
| 原文出处 | http://ac.els-cdn.com/S0014482715001214/1-s2.0-S0014482715001214-main.pdf?_tid=1ee73b7c-98d6-11e5-85fc-00000aacb35e&acdnat=1449048291_79e3369c0dab2980bb790b78634d0dc0 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7551]  |
| 专题 | 深圳先进技术研究院_南沙所 |
| 作者单位 | EXPERIMENTAL CELL RESEARCH |
| 推荐引用方式 GB/T 7714 | Lu YF,Zhang L,Waye MM,et al. MiR-218 mediates tumorigenesis and metastasis: Perspectives and implications[J]. EXPERIMENTAL CELL RESEARCH,2015. |
| APA | Lu YF,Zhang L,Waye MM,Fu WM,&Zhang JF..(2015).MiR-218 mediates tumorigenesis and metastasis: Perspectives and implications.EXPERIMENTAL CELL RESEARCH. |
| MLA | Lu YF,et al."MiR-218 mediates tumorigenesis and metastasis: Perspectives and implications".EXPERIMENTAL CELL RESEARCH (2015). |
入库方式： OAI收割
来源：深圳先进技术研究院
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