Extracting elastic properties and prestress of a cell using atomic force microscopy
文献类型:期刊论文
作者 | Chunyu Zhang; Y.W.Zhang |
刊名 | Journal of Materials Research
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出版日期 | 2009 |
卷号 | 24期号:3页码:1167-1171 |
英文摘要 | An analytical Solution was derived for the indentation of a cell using atomic force microscopy. It was found that the contribution of the cell membrane to the overall indentation stiffness is dependent oil the size of the indenter. When a small indenter [for example, an atomic force microscopy (AFM) tip] is used to probe the mechanical properties of cells, the cell membrane and its prestress were important in interpreting indentation data. The Solution allows the partition of contributions From the membrane and the interior soft phase. The apparent elastic modulus of the cell and the prestress of the cellmembrane can be extracted. In addition, the modulus of the cell membrane could be estimated from the extracted apparent modulus if the interior soft phase of the cell was known and vice versa. However, when a large indenter is used (for example, a microbead attached to the cantilever beam of the AFM), the contribution of the cell membrane is negligible. |
收录类别 | SCI |
原文出处 | http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=7950676 |
语种 | 英语 |
源URL | [http://ir.siat.ac.cn:8080/handle/172644/2667] ![]() |
专题 | 深圳先进技术研究院_其他 |
作者单位 | Journal of Materials Research |
推荐引用方式 GB/T 7714 | Chunyu Zhang,Y.W.Zhang. Extracting elastic properties and prestress of a cell using atomic force microscopy[J]. Journal of Materials Research,2009,24(3):1167-1171. |
APA | Chunyu Zhang,&Y.W.Zhang.(2009).Extracting elastic properties and prestress of a cell using atomic force microscopy.Journal of Materials Research,24(3),1167-1171. |
MLA | Chunyu Zhang,et al."Extracting elastic properties and prestress of a cell using atomic force microscopy".Journal of Materials Research 24.3(2009):1167-1171. |
入库方式: OAI收割
来源:深圳先进技术研究院
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