Controlled assembly of gold nanoparticles through antibody recognition: Study and utilizing the effect of particle size on interparticle distance
文献类型：期刊论文
| 作者 | Guohua Zhou; Yizhen Liu; Ming Luo; Xiuhong Li; Qinfeng Xu; Xinghu Ji; Zhike He |
| 刊名 | LANGMUIR
 |
| 出版日期 | 2013 |
| 英文摘要 | An assembly of gold nanoparticle through the recognition of unmodified antibody was developed. The use of peptide (Cys-Ala-Leu-Asn-Asn) as ligands to stabilize and functionalize gold nanoparticles provides technical and operational convenience. These peptide-capped particles in different sizes are recognized by antibody and assembly to form dimers and expanded hybrid material by controlling the conditions. The interparticle spacing of these assemblies was well studied with small-angle X-ray scattering measurements, and it was found that the interparticle spacing is inversely dependent on the particle size. This relationship of interparticle spacing and particle size is closely related to the structure of antibody linker. Therefore, analyzing the interparticle spacing of assemblies can reveal the equilibrium configuration of IgG. Based on the investigation, the Fab–Fab angle of IgG is obtained to be ≈102° and the Fab arms are ≈7.8 nm. These results provide new experimental data on the structure of flexible IgG. |
| 收录类别 | SCI |
| 原文出处 | http://pubs.acs.org/doi/abs/10.1021/la400404g |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/5239]  |
| 专题 | 深圳先进技术研究院_其他 |
| 作者单位 | LANGMUIR |
| 推荐引用方式 GB/T 7714 | Guohua Zhou,Yizhen Liu,Ming Luo,et al. Controlled assembly of gold nanoparticles through antibody recognition: Study and utilizing the effect of particle size on interparticle distance[J]. LANGMUIR,2013. |
| APA | Guohua Zhou.,Yizhen Liu.,Ming Luo.,Xiuhong Li.,Qinfeng Xu.,...&Zhike He.(2013).Controlled assembly of gold nanoparticles through antibody recognition: Study and utilizing the effect of particle size on interparticle distance.LANGMUIR. |
| MLA | Guohua Zhou,et al."Controlled assembly of gold nanoparticles through antibody recognition: Study and utilizing the effect of particle size on interparticle distance".LANGMUIR (2013). |
入库方式： OAI收割
来源：深圳先进技术研究院
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