Preliminary study of b-value dependence of MR diffusion tensor imaging measurements in myocardium structure characterization
文献类型：会议论文
| 作者 | Wu, Yin; Zou, Chao; Zhang, Na; Xie, Guoxi; Liu, Xin; Feng, Fei; Liu, Yang |
| 出版日期 | 2010 |
| 会议名称 | 3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010 |
| 会议地点 | Yantai, China |
| 英文摘要 | MR diffusion tensor imaging (DTI) has been successfully used to characterize myocardium structure in numerous studies. Recently, conventional DTI has been demonstrated to need optimization in describing brain microstructure as water diffusion in such kind of complex biological tissue is not a free Gaussian process, which conflicts with the basic assumption of conventional DTI that diffusion weighted signal decays with diffusion sensitivity in a monoexponential behavior. In this study, dependence of DTI measurements on diffusion sensitivity factor (i.e., b-value) was assessed on left ventricular (LV) myocardium in a normal porcine heart using ex vivo DTI. Fractional anisotropy (FA), trace apparent diffusion coefficient (trace ADC), axial diffusivity (λ//) and radial diffusivity (λ⊥) were calculated and compared among different b-values (800-2000 s/mm2) as well as monoexponential fitting (Monoexp) via all the b-values. Results show that diffusivities, including trace ADC, λ// and λ⊥, varied significantly with b-values. But no substantial alteration of FA was found among different b-values. These very preliminary experimental results may imply the effect of b-value on characterization of myocardium structural diffusion properties to some extend, and suggests the potential necessity to optimize b-value for myocardium structure assessment and alteration monitoring in both normal and pathological states using DTI. |
| 收录类别 | EI |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/3001]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | 2010 |
| 推荐引用方式 GB/T 7714 | Wu, Yin,Zou, Chao,Zhang, Na,et al. Preliminary study of b-value dependence of MR diffusion tensor imaging measurements in myocardium structure characterization[C]. 见:3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010. Yantai, China. |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。