Application of ultrasonic particle imaging velocimetry to flows of rat arteries atherosclerosis model
文献类型：会议论文
| 作者 | Yiheng Zhu; Ming Qian; Lili Niu; Guangwen Lu; Hairong Zheng |
| 出版日期 | 2013 |
| 会议名称 | 2013 IEEE International Conference on Medical Imaging Physics and Engineering, ICMIPE 2013 |
| 会议地点 | Shenyang, China |
| 英文摘要 | Purpose: Hemodynamic changes in vascular stenosis could affect blood flow component of flow distribution which changed the nature of vascular smooth muscle cells. Observation and analysis of blood flow in the heart disease have important clinical significance of treatments of arterial stenosis. Method: The ultrasonic particle image velocimetry (Echo PIV) technique is appropriate for measuring blood flows by taking advantage of PIV and B-mode ultrasound contrast imaging. This study established animal models. 60 healthy male SD rats were selected and divided into 6 groups. On the 21st day of establishment of vascular stenosis model and drug treatment, the left common carotid artery of rats in groups was observed with ultrasound biomicroscopy. Morphological and hemodynamic changes in the normal blood vessels and the stenosis of the lumen were observed with application of Echo PIV. The reliability of Echo PIV was verified by comparing with ultrasonic Doppler velocimetry methods. Conclusion: Animal studies concerning arterial flows of rats show that the Echo PIV-measured peak and average velocities within several cardiac cycles are about 5-10% and 2-8% below the values measured by the ultrasonic spectral Doppler, respectively. Echo PIV method could directly assess whole field hemodynamic changes of normal blood vessels and vascular stenosis with non-invasion and real-time monitoring of restenosis therapy. It further to explore the prevention and treatment of restenosis and vascular plaque rupture mechanism. |
| 收录类别 | EI |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/4937]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | 2013 |
| 推荐引用方式 GB/T 7714 | Yiheng Zhu,Ming Qian,Lili Niu,et al. Application of ultrasonic particle imaging velocimetry to flows of rat arteries atherosclerosis model[C]. 见:2013 IEEE International Conference on Medical Imaging Physics and Engineering, ICMIPE 2013. Shenyang, China. |
入库方式： OAI收割
来源：深圳先进技术研究院
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