Integrated intravascular ultrasound and optical-resolution photoacoustic microscopy with a 1-mm-diameter catheter
文献类型：会议论文
| 作者 | Xiaosong Bai; Xiaojing Gong; Riqiang Lin; William Hau; Liang Song |
| 出版日期 | 2014 |
| 会议名称 | Photons Plus Ultrasound: Imaging and Sensing 2014 |
| 会议地点 | San Francisco, CA |
| 英文摘要 | Intravascular ultrasound (IVUS) plays a vital role in assessing the severity of atherosclerosis and has greatly enriched our knowledge on atherosclerotic plaques. However, it mainly reveals the structural information of plaques. In contrast, spectroscopic and molecular photoacoustic imaging can potentially improve plaque composition identification, inflammation detection, and ultimately the stratification of plaque vulnerability and risk. In this work, we developed an integrated intravascular ultrasound and optical-resolution photoacoustic microscopy (IVUS-PAM) system with a single catheter as small as 1 mm in diameter, comparable to that of existing clinical IVUS catheters. In addition, by using a GRIN lens to focus the excitation laser pulse, the system provides an optical-diffraction limited photoacoustic lateral resolution as fine as 19.6 micrometers, similar to 10-fold finer than that of conventional intravascular photoacoustic imaging and existing IVUS technology. The system employs a custom-made miniaturized single-element ultrasonic transducer with a dimension of similar to 0.5 mm, a centre frequency of similar to 40 MHz, and a fractional bandwidth of similar to 60%. The IVUS-PAM can simultaneously acquire co-registered IVUS images with an axial resolution of similar to 40 micrometers and a lateral resolution of similar to 200 micrometers. In the future, IVUS-PAM may open up new opportunities for improved high-resolution vulnerable plaque imaging and image-guided stent deployment. |
| 收录类别 | EI |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/5888]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | 2014 |
| 推荐引用方式 GB/T 7714 | Xiaosong Bai,Xiaojing Gong,Riqiang Lin,et al. Integrated intravascular ultrasound and optical-resolution photoacoustic microscopy with a 1-mm-diameter catheter[C]. 见:Photons Plus Ultrasound: Imaging and Sensing 2014. San Francisco, CA. |
入库方式： OAI收割
来源：深圳先进技术研究院
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