Chirp excitation technique to enhance microbubble displacement induced by ultrasound radiation force
文献类型：期刊论文
| 作者 | Hu Yi; Zhang Dong; Zheng Hairong; Gong Xiufen |
| 刊名 | Journal of the Acoustical Society of America
 |
| 出版日期 | 2009 |
| 卷号 | 125期号:3页码:1410-1415 |
| 英文摘要 | Ultrasound radiation force has been proposed to increase the targeting efficiency in ultrasonic molecular imaging and drug delivery. A chirp excitation technique is proposed to increase the radiation force induced microbubble displacement and might potentially be used for enhancing the targeting efficiency of microbubble clouds. In this study, a modified Rayleigh-Plesset equation is used to estimate the radius-time behavior of insonified microbubbles, and the translation of insonified microbubbles is calculated by using the particle trajectory equation. Simulations demonstrate that the chirp excitation is superior to the sinusoidal one in displacing microbubbles with a wide-size distribution, and that the performance is dependent on the parameters of the chirp signal such as the center frequency and frequency range. For Gaussian size distributed microbubble clouds with mean diameter of 3.5 μm and variance of 1, a 2.25 MHz chirp with frequency range of 1.5 MHz induces about 59.59% more microbubbles over a distance of 10 μm during 200 μs insonification, compared to a 2.25 MHz sinusoidal excitation with equal acoustic pressure. © 2009 Acoustical Society of America. |
| 收录类别 | SCI |
| 原文出处 | http://www.ncbi.nlm.nih.gov/pubmed/19275298 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/2527]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | Journal of the Acoustical Society of America |
| 推荐引用方式 GB/T 7714 | Hu Yi,Zhang Dong,Zheng Hairong,et al. Chirp excitation technique to enhance microbubble displacement induced by ultrasound radiation force[J]. Journal of the Acoustical Society of America,2009,125(3):1410-1415. |
| APA | Hu Yi,Zhang Dong,Zheng Hairong,&Gong Xiufen.(2009).Chirp excitation technique to enhance microbubble displacement induced by ultrasound radiation force.Journal of the Acoustical Society of America,125(3),1410-1415. |
| MLA | Hu Yi,et al."Chirp excitation technique to enhance microbubble displacement induced by ultrasound radiation force".Journal of the Acoustical Society of America 125.3(2009):1410-1415. |
入库方式： OAI收割
来源：深圳先进技术研究院
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