Marine Cyclotripeptide X-13 Promotes Angiogenesis in Zebrafish and Human Endothelial Cells via PI3K/Akt/eNOS Signaling Pathways
文献类型：期刊论文
| 作者 | Xi-Lin Lu; Zhong-Liang Xu; Xiao-Li Yao; Feng-Juan Su; Cheng-Hui Ye; Jing Li; Yong-Cheng Lin; Guang-Lei Wang; Jin-Sheng Zeng; Ru-Xun Huang |
| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2012 |
| 英文摘要 | Cyclotripeptide X-13 is a core of novel marine compound xyloallenoide A isolated from mangrove fungus Xylaria sp. (no. 2508). We found that X-13 dose-dependently induced angiogenesis in zebrafish embryos and in human endothelial cells, which was accompanied by increased phosphorylation of eNOS and Akt and NO release. Inhibition of PI3K/Akt/eNOS by LY294002 or L-NAME suppressed X-13-induced angiogenesis. The present work demonstrates that X-13 promotes angiogenesis via PI3K/Akt/eNOS pathways |
| 收录类别 | SCI |
| 原文出处 | http://www.mdpi.com/1660-3397/10/6/1307/htm |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/3970]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | MARINE DRUGS |
| 推荐引用方式 GB/T 7714 | Xi-Lin Lu,Zhong-Liang Xu,Xiao-Li Yao,et al. Marine Cyclotripeptide X-13 Promotes Angiogenesis in Zebrafish and Human Endothelial Cells via PI3K/Akt/eNOS Signaling Pathways[J]. MARINE DRUGS,2012. |
| APA | Xi-Lin Lu.,Zhong-Liang Xu.,Xiao-Li Yao.,Feng-Juan Su.,Cheng-Hui Ye.,...&Zhong Pei.(2012).Marine Cyclotripeptide X-13 Promotes Angiogenesis in Zebrafish and Human Endothelial Cells via PI3K/Akt/eNOS Signaling Pathways.MARINE DRUGS. |
| MLA | Xi-Lin Lu,et al."Marine Cyclotripeptide X-13 Promotes Angiogenesis in Zebrafish and Human Endothelial Cells via PI3K/Akt/eNOS Signaling Pathways".MARINE DRUGS (2012). |
入库方式： OAI收割
来源：深圳先进技术研究院
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