Effects of different therapeutic ultrasound intensities on fracture healing in rats
文献类型：期刊论文
| 作者 | CHAK-HEI FUNG; WING-HOI CHEUNG; NEILL M. POUNDER; F. JAVIER DE ANA; ANDREW HARRISON; KWOK-SUI LEUNG |
| 刊名 | ULTRASOUND IN MEDICINE AND BIOLOGY
 |
| 出版日期 | 2012 |
| 英文摘要 | Low-intensity pulsed ultrasound (LIPUS) with I-SATA = 30 mW/cm(2) has been proven in facilitating fracture healing, which the spatial average intensity over the on period (I-SATP) equals 150 mW/cm(2). As active ultrasound wave is only delivered during the on period, we postulate 150 mW/cm(2) is responsible for the beneficial effect of LIPUS. In this study, we compare the biologic effects of 30 mW/cm(2) and 150 mW/cm(2). We propose I-SATA = 150 mW/cm(2) could further enhance fracture healing process. Closed femoral fractured Sprague-Dawley rats were randomized into control, LIPUS-30 (30 mW/cm(2)) and LIPUS-150 (150 mW/cm(2)) groups. Weekly radiographs and endpoint microCT, histomorphometry, and biomechanical tests were performed. The results show that LIPUS-30 had significantly higher low-density bone volume fraction and woven bone percentage than that of control and LIPUS-150 in microCT and histologic measurements, respectively. Mechanically, failure torque of LIPUS-30 was significantly higher than control and LIPUS-150 at week 6. In conclusion, LIPUS at I-SATA = 150 mW/cm(2) did not further enhance fracture healing. (E-mail: louis@ort.cuhk.edu.hk) (C) 2012 World Federation for Ultrasound in Medicine & Biology. |
| 收录类别 | SCI |
| 原文出处 | http://ac.els-cdn.com/S0301562912000543/1-s2.0-S0301562912000543-main.pdf?_tid=da3e0c3a-0933-11e5-b55b-00000aacb361&acdnat=1433255589_23dcf67d3a7b755e39a760da29795707 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/4015]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | ULTRASOUND IN MEDICINE AND BIOLOGY |
| 推荐引用方式 GB/T 7714 | CHAK-HEI FUNG,WING-HOI CHEUNG,NEILL M. POUNDER,et al. Effects of different therapeutic ultrasound intensities on fracture healing in rats[J]. ULTRASOUND IN MEDICINE AND BIOLOGY,2012. |
| APA | CHAK-HEI FUNG,WING-HOI CHEUNG,NEILL M. POUNDER,F. JAVIER DE ANA,ANDREW HARRISON,&KWOK-SUI LEUNG.(2012).Effects of different therapeutic ultrasound intensities on fracture healing in rats.ULTRASOUND IN MEDICINE AND BIOLOGY. |
| MLA | CHAK-HEI FUNG,et al."Effects of different therapeutic ultrasound intensities on fracture healing in rats".ULTRASOUND IN MEDICINE AND BIOLOGY (2012). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。