Screening features to improve the class prediction of acute myeloid leukemia and myelodysplastic syndrome
文献类型：期刊论文
| 作者 | Kaishi Li; Meixue Yang; Gaurav Sablok; Jianping Fan; Fengfeng Zhou |
| 刊名 | Gene
 |
| 出版日期 | 2013 |
| 英文摘要 | After more than three decades of intensive investigations, the underpinning mechanism of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) pathogenesis still remains largely uncharacterized, and their diagnosis relies heavily on the subjective factors. Recently gene expression profiling technique showed significant improvement in classifying some subtypes of AML, but the model's discriminating power of MDS from AML is still in its infancy. Feature selection plays an important role in the classification of the samples on the basis of the gene expression profiles. Our hypothesis explains that a better choice of features could improve the classification of the diseased and normal stage samples, and the potential application of feature screening to produce feature sets, with better accuracies and lowest number of embedded features. The observed results suggest that feature selection proves to be an essential and affirmative step in the biomedical data mining models based on gene expression profiles. (c) 2012 Elsevier B.V. All rights reserved. |
| 收录类别 | SCI |
| 原文出处 | http://ac.els-cdn.com/S0378111912012322/1-s2.0-S0378111912012322-main.pdf?_tid=f276f526-086d-11e5-8505-00000aab0f02&acdnat=1433170581_219451e52a21cb98f662efabcb3a5dca |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/4844]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | Gene |
| 推荐引用方式 GB/T 7714 | Kaishi Li,Meixue Yang,Gaurav Sablok,et al. Screening features to improve the class prediction of acute myeloid leukemia and myelodysplastic syndrome[J]. Gene,2013. |
| APA | Kaishi Li,Meixue Yang,Gaurav Sablok,Jianping Fan,&Fengfeng Zhou.(2013).Screening features to improve the class prediction of acute myeloid leukemia and myelodysplastic syndrome.Gene. |
| MLA | Kaishi Li,et al."Screening features to improve the class prediction of acute myeloid leukemia and myelodysplastic syndrome".Gene (2013). |
入库方式： OAI收割
来源：深圳先进技术研究院
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