Intravascular optical-resolution photoacoustic tomography with a 1.1 mm diameter catheter
文献类型:期刊论文
作者 | Xiaosong Bai; Xiaojing Gong; William Hau; Riqiang Lin; Jiaxiang Zheng; Chengbo Liu; Chengzhi Zeng; Xin Zou; Hairong Zheng; Liang Song |
刊名 | PLOS ONE
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出版日期 | 2014 |
英文摘要 | Photoacoustic imaging is an emerging technology that can provide anatomic, functional, and molecular information about biological tissue. Intravascular spectroscopic and molecular photoacoustic imaging can potentially improve the identification of atherosclerotic plaque composition, the detection of inflammation, and ultimately the risk stratification of atherosclerosis. In this study, a first-of-its-kind intravascular optical-resolution photoacoustic tomography (OR-PAT) system with a 1.1 mm diameter catheter is developed, offering optical-diffraction limited transverse resolution as fine as 19.6 mu m, similar to 10-fold finer than that of conventional intravascular photoacoustic and ultrasonic imaging. To offer complementary imaging information and depth, the system also acquires co-registered intravascular ultrasound images in parallel. Imaging of an iliac stent and a lipid phantom shows that the high resolution and contrast of OR-PAT can enable improved stent implantation guidance and lipid identification. In the future, these capabilities may ultimately improve the diagnosis and interventional treatment of vulnerable atherosclerotic plaques, which are prone to cause thrombotic complications such as myocardial infarction and stroke. |
收录类别 | SCI |
原文出处 | http://www.plosone.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pone.0092463&representation=PDF |
语种 | 英语 |
源URL | [http://ir.siat.ac.cn:8080/handle/172644/5784] ![]() |
专题 | 深圳先进技术研究院_医工所 |
作者单位 | PLOS ONE |
推荐引用方式 GB/T 7714 | Xiaosong Bai,Xiaojing Gong,William Hau,et al. Intravascular optical-resolution photoacoustic tomography with a 1.1 mm diameter catheter[J]. PLOS ONE,2014. |
APA | Xiaosong Bai.,Xiaojing Gong.,William Hau.,Riqiang Lin.,Jiaxiang Zheng.,...&Liang Song.(2014).Intravascular optical-resolution photoacoustic tomography with a 1.1 mm diameter catheter.PLOS ONE. |
MLA | Xiaosong Bai,et al."Intravascular optical-resolution photoacoustic tomography with a 1.1 mm diameter catheter".PLOS ONE (2014). |
入库方式: OAI收割
来源:深圳先进技术研究院
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