Reflection-mode in vivo photoacoustic microscopy with subwavelength lateral resolution
文献类型：期刊论文
| 作者 | Wei Song; Wei Zheng; Ruimin Liu; Riqiang Lin; Hongtao Huang; Xiaojing Gong; Shousheng Yang; Rui Zhang; Liang Song |
| 刊名 | BIOMEDICAL OPTICS EXPRESS
 |
| 出版日期 | 2014 |
| 英文摘要 | We developed a reflection-mode subwavelength-resolution photoacoustic microscopy system capable of imaging optical absorption contrast in vivo. The simultaneous high-resolution and reflection-mode imaging capacity of the system was enabled by delicately configuring a miniature high-frequency ultrasonic transducer tightly under a water-immersion objective with numerical aperture of 1.0. At 532-nm laser illumination, the lateral resolution of the system was measured to be ~320 nm. With this system, subcellular structures of red blood cells and B16 melanoma cells were resolved ex vivo; microvessels, including individual capillaries, in a mouse ear were clearly imaged label-freely in vivo, using the intrinsic optical absorption from hemoglobin. The current study suggests that, the optical-absorption contrast, subwavelength resolution, and reflection-mode ability of the developed photoacoustic microscopy may empower a wide range of biomedical studies for visualizing cellular and/or subcellular structures. |
| 收录类别 | SCI |
| 原文出处 | https://www.osapublishing.org/boe/abstract.cfm?uri=boe-5-12-4235 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/5786]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | BIOMEDICAL OPTICS EXPRESS |
| 推荐引用方式 GB/T 7714 | Wei Song,Wei Zheng,Ruimin Liu,et al. Reflection-mode in vivo photoacoustic microscopy with subwavelength lateral resolution[J]. BIOMEDICAL OPTICS EXPRESS,2014. |
| APA | Wei Song.,Wei Zheng.,Ruimin Liu.,Riqiang Lin.,Hongtao Huang.,...&Liang Song.(2014).Reflection-mode in vivo photoacoustic microscopy with subwavelength lateral resolution.BIOMEDICAL OPTICS EXPRESS. |
| MLA | Wei Song,et al."Reflection-mode in vivo photoacoustic microscopy with subwavelength lateral resolution".BIOMEDICAL OPTICS EXPRESS (2014). |
入库方式： OAI收割
来源：深圳先进技术研究院
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