Low-grade myxofibrosarcoma following a metal implantation in femur: a case report
文献类型：期刊论文
| 作者 | Weisong Li; Dan Li; Xiansen Zhu; Shaohui Lu; Chunlei He; Qingchun Yang |
| 刊名 | DIAGNOSTIC PATHOLOGY
 |
| 出版日期 | 2014 |
| 英文摘要 | Myxofibrosarcoma is a myxoid variant of malignant fibrous histiocytoma that most commonly involves the extremities of elderly people. However, a primary myxofibrosarcoma with bone invasion in young adults is extremely rare. Herein, we report the case of a 31-year-old male with a gradually enlarging left thigh mass, who had a history of left femur fracture and received an open reduction and internal fixation with titanium alloy plates and screws 33 months previously. Imaging investigations revealed an irregularly shaped soft tissue mass around the left femur shaft and a partial bone defect in the middle one-third of the left femur. Pathological examination of the resected specimen showed a multi-nodular appearance, abundant myxoid matrix and elongated curvilinear capillaries. Immunohistochemical studies revealed that the tumor cells was positive for VIM and MDM2, and was negative for CK, MSA, SMA, DES, S-100 and CD34. Labeling index of Ki-67 was 25%. Based on the morphological finding and immunostaining, it was diagnosed as a low-grade myxofibrosarcoma. The clinical and imaging examinations did not reveal the evidence of a primary cancer elsewhere, and the patient had no personal or family history of malignancy. To our knowledge, this is the first case of a primary myxofibrosarcoma developed following a fracture and metal implantation in young adults. |
| 收录类别 | SCI |
| 原文出处 | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926977/pdf/1746-1596-9-6.pdf |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/5843]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | DIAGNOSTIC PATHOLOGY |
| 推荐引用方式 GB/T 7714 | Weisong Li,Dan Li,Xiansen Zhu,et al. Low-grade myxofibrosarcoma following a metal implantation in femur: a case report[J]. DIAGNOSTIC PATHOLOGY,2014. |
| APA | Weisong Li,Dan Li,Xiansen Zhu,Shaohui Lu,Chunlei He,&Qingchun Yang.(2014).Low-grade myxofibrosarcoma following a metal implantation in femur: a case report.DIAGNOSTIC PATHOLOGY. |
| MLA | Weisong Li,et al."Low-grade myxofibrosarcoma following a metal implantation in femur: a case report".DIAGNOSTIC PATHOLOGY (2014). |
入库方式： OAI收割
来源：深圳先进技术研究院
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