Quantification of three-dimensional computed tomography angiography for evaluating coronary luminal stenosis using digital subtraction angiography as the standard of reference
文献类型：期刊论文
| 作者 | Guo Wei; Liu Xin; Gao Zhifan; Pirbhulal Sandeep; Huang Wenhua; Lin WanHua; Zhang Heye; Tan Ning; Zhang YuanTing |
| 刊名 | BIOMEDICAL ENGINEERING ONLINE
 |
| 出版日期 | 2015 |
| 英文摘要 | Objective: We sought to evaluate the accuracy of quantitative three-dimensional (3D) CT angiography (CTA) for the assessment of coronary luminal stenosis using digital subtraction angiography (DSA) as the standard of reference. Method: Twenty-three patients with 54 lesions were referred for CTA followed by DSA. The CTA scans were performed with 256-slice spiral CT. 3D CTA were reconstructed from two-dimensional CTA imaging sequences in order to extract the following quantitative indices: minimal lumen diameter, percent diameter stenosis (% DS), minimal lumen area, and percent area stenosis (% AS). Correlation and limits of agreement were calculated using Pearson correlation and Bland-Altman analysis, respectively. The diagnostic performance and the diagnostic concordance of 3D CTAderived anatomic parameters (% DS, % AS) for the detection of severe coronary arterial stenosis (as assessed by DSA) were presented as sensitivity, specificity, diagnostic accuracy, and Kappa statistics. Of which vessels with % DS >50% or with % AS >75% were identified as severe coronary arterial lesions. Result: The correlations of the anatomic parameters between 3D CTA and DSA were significant (r = 0.51-0.74, P < 0.001). Bland-Altman analysis confirmed that the mean differences were small (from -1.11 to 27.39%), whereas the limits of agreement were relatively wide (from +/- 28.07 to +/- 138.64%). Otherwise, the diagnostic accuracy (74.1% with 58.3% sensitivity and 86.7% specificity for DS%; 74.1% with 45.8% sensitivity and 96.7% specificity for % AS) and the diagnostic concordance (k = 0.46 for DS%; 0.45 for % AS) of 3D CTA-derived anatomic parameters for the detection of severe stenosis were moderate. Conclusion: 3D advanced imaging reconstruction technique is a helpful tool to promote the use of CTA as an alternative to assess luminal stenosis in clinical practice. |
| 收录类别 | SCI |
| 原文出处 | http://www.biomedical-engineering-online.com/content/14/1/50 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7051]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | BIOMEDICAL ENGINEERING ONLINE |
| 推荐引用方式 GB/T 7714 | Guo Wei,Liu Xin,Gao Zhifan,et al. Quantification of three-dimensional computed tomography angiography for evaluating coronary luminal stenosis using digital subtraction angiography as the standard of reference[J]. BIOMEDICAL ENGINEERING ONLINE,2015. |
| APA | Guo Wei.,Liu Xin.,Gao Zhifan.,Pirbhulal Sandeep.,Huang Wenhua.,...&Zhang YuanTing.(2015).Quantification of three-dimensional computed tomography angiography for evaluating coronary luminal stenosis using digital subtraction angiography as the standard of reference.BIOMEDICAL ENGINEERING ONLINE. |
| MLA | Guo Wei,et al."Quantification of three-dimensional computed tomography angiography for evaluating coronary luminal stenosis using digital subtraction angiography as the standard of reference".BIOMEDICAL ENGINEERING ONLINE (2015). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。