Increased interhemispheric functional connectivity in college students with non-clinical depressive symptoms in resting state
文献类型：期刊论文
| 作者 | Wei XinHua; Ren JiLiang; Liu WenHua; Yang RuiMeng; Xu XiangDong; Liu Jun; Guo YongMei; Yu ShaoDe; Lai LiSha; Xie YaoQin |
| 刊名 | NEUROSCIENCE LETTERS
 |
| 出版日期 | 2015 |
| 英文摘要 | The underlying neural basis of non-clinical depressive symptoms (nCDSs) remains unclear. Interhemispheric functional connectivity has been suggested as one of the most robust characteristics of brain's intrinsic functional architecture. Here, we investigated the functional connectivity between homotopic points in the brain using the voxel-mirrored homotopic connectivity (VMHC) approach. We performed VMHC analysis on resting-state functional magnetic resonance imaging (rs-fMRI) data from 17 individuals with nCDSs and 20 healthy controls (HCs) who were enrolled from a sample of 1105 college students. We found increased VMHCs in the bilateral posterior cerebellum and fusiform gyrus in nCDSs subjects compared with HCs. Furthermore, receiver operating characteristic (ROC) curves indicated that VMHC values in the posterior cerebellum lobes could use to differente nCDSs from HCs [area under the curve (AUC), 0.756; p < 0.01]. We suggest increased VMHCs indicate a possible compensatory mechanism involved in the pathophysiology of nCDSs. VMHC values of the posterior cerebellum lobes might serve as a reliable biomarker for identifying nCDSs. (C) 2015 Elsevier Ireland Ltd. All rights reserved. |
| 收录类别 | SCI |
| 原文出处 | http://www.ncbi.nlm.nih.gov/pubmed/25596443 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7101]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | NEUROSCIENCE LETTERS |
| 推荐引用方式 GB/T 7714 | Wei XinHua,Ren JiLiang,Liu WenHua,et al. Increased interhemispheric functional connectivity in college students with non-clinical depressive symptoms in resting state[J]. NEUROSCIENCE LETTERS,2015. |
| APA | Wei XinHua.,Ren JiLiang.,Liu WenHua.,Yang RuiMeng.,Xu XiangDong.,...&Jiang XinQing.(2015).Increased interhemispheric functional connectivity in college students with non-clinical depressive symptoms in resting state.NEUROSCIENCE LETTERS. |
| MLA | Wei XinHua,et al."Increased interhemispheric functional connectivity in college students with non-clinical depressive symptoms in resting state".NEUROSCIENCE LETTERS (2015). |
入库方式： OAI收割
来源：深圳先进技术研究院
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