Double-scattering/reflection in a Single Nanoparticle for Intensified Ultrasound Imaging
文献类型：期刊论文
| 作者 | Zhang Kun; Chen Hangrong; Guo Xiasheng; Zhang Dong; Zheng Yuanyi; Zheng Hairong; Shi Jianlin |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2015 |
| 英文摘要 | Ultrasound contrast agents (UCAs) designed by the conventional composition-based strategy, often suffer from relatively low ultrasound utilization efficiency. In this report, a structure-based design concept of double-scattering/reflection in a single nanoparticle for enhancing ultrasound imaging has been proposed. To exemplify this concept, a rattle-type mesoporous silica nanostructure (MSN) with two contributing interfaces has been employed as the ideal model. Contributed by double-scattering/reflection interfaces, the rattle-type MSN, as expected, performs much better in in vitro and in vivo ultrasound imaging than the other two nanostructures (solid and hollow) containing only one scattering/reflection interface. More convincingly, related acoustic measurements and simulation calculations also confirm this design concept. Noticeably, the rattle-type MSN has also been demonstrated capable of improving intracellular ultrasound molecular imaging. As a universal method, the structure-design concept can extend to guide the design of new generation UCAs with many other compositions and similar structures (e.g., heterogeneous rattle-type, double-shelled). |
| 收录类别 | SCI |
| 原文出处 | http://www.nature.com/articles/srep08766 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7142]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | SCIENTIFIC REPORTS |
| 推荐引用方式 GB/T 7714 | Zhang Kun,Chen Hangrong,Guo Xiasheng,et al. Double-scattering/reflection in a Single Nanoparticle for Intensified Ultrasound Imaging[J]. SCIENTIFIC REPORTS,2015. |
| APA | Zhang Kun.,Chen Hangrong.,Guo Xiasheng.,Zhang Dong.,Zheng Yuanyi.,...&Shi Jianlin.(2015).Double-scattering/reflection in a Single Nanoparticle for Intensified Ultrasound Imaging.SCIENTIFIC REPORTS. |
| MLA | Zhang Kun,et al."Double-scattering/reflection in a Single Nanoparticle for Intensified Ultrasound Imaging".SCIENTIFIC REPORTS (2015). |
入库方式： OAI收割
来源：深圳先进技术研究院
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