Efficient Method for Analyzing MR Real-Time Cines: Toward Accurate Quantification of Left Ventricular Function
文献类型：期刊论文
| 作者 | Yin Wu; Ke Jiang; Na Zhang; Yinzhu Gao; Yucheng Chen; Hairong Zheng; Xin Liu; Yiu-Cho Chung |
| 刊名 | JOURNAL OF MAGNETIC RESONANCE IMAGING
 |
| 出版日期 | 2015 |
| 英文摘要 | Background: To develop and assess an efficient method to identify end-expiratory end-diastolic (ED) and end-systolic (ES) images for accurate quantification of left ventricular (LV) function in real-time cine imaging. Methods: ECG-free free-breathing real-time cine imaging was performed on short-axis slices of thirteen healthy volunteers at 3 Tesla. K-means cluster segmentation was applied to delineate the endocardial contour, from which the LV centroid and cavity area were determined in each cine image. LV centroid displacement along the superior-inferior direction was filtered to extract respiratory motion in each slice. End-expiratory ED and ES images were then identified and used for LV function quantification. Accuracy was evaluated with that measured from the slice-matched standard ECG-gated breathhold segmented cines using two-tail paired Student's t-tests, linear regression analyses and Bland-Altman plots. Intra-and interobserver variability was calculated for each imaging technique.Results: Qualitatively, end-expiratory ED and ES images identified with the proposed method agreed with those determined by frame-by-frame visual inspection in 97.5% of cases (P>0.05). Quantitatively, good agreement of LV function indices between the real-time cine and the standard segmented cine was observed with averaged differences of 0.1 +/- 0.9 g for myocardium mass, -0.3 +/- 1.0 mL for ED volume, 0.2 +/- 1.2 mL for ES volume, -0.2 +/- 1.3 mL for stroke volume, and -0.3 +/- 0.8% for ejection fraction. Paired LV function values exhibited strong correlation (r >= 0.96) and no significant difference (P>0.05). The real-time cine and the standard segmented cine showed similar intra- (1.2-3.3% and 1.1-2.8%, respectively) and interobserver variability (2.6-6.9% and 1.8-4.8%, respectively) with all P-values>0.05. All the variability was comparable with published results. Conclusion: Compared with the laborious frame-by-frame visual inspection, as conventionally adopted, the proposed method is efficient in analyzing real-time cines for the accurate quantification of LV function without excessively manual interactions. |
| 收录类别 | SCI |
| 原文出处 | http://onlinelibrary.wiley.com/doi/10.1002/jmri.24869/full |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7166]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | JOURNAL OF MAGNETIC RESONANCE IMAGING |
| 推荐引用方式 GB/T 7714 | Yin Wu,Ke Jiang,Na Zhang,et al. Efficient Method for Analyzing MR Real-Time Cines: Toward Accurate Quantification of Left Ventricular Function[J]. JOURNAL OF MAGNETIC RESONANCE IMAGING,2015. |
| APA | Yin Wu.,Ke Jiang.,Na Zhang.,Yinzhu Gao.,Yucheng Chen.,...&Yiu-Cho Chung.(2015).Efficient Method for Analyzing MR Real-Time Cines: Toward Accurate Quantification of Left Ventricular Function.JOURNAL OF MAGNETIC RESONANCE IMAGING. |
| MLA | Yin Wu,et al."Efficient Method for Analyzing MR Real-Time Cines: Toward Accurate Quantification of Left Ventricular Function".JOURNAL OF MAGNETIC RESONANCE IMAGING (2015). |
入库方式： OAI收割
来源：深圳先进技术研究院
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