中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
ACC and IPL networks in the perception of the faces of parents during selective tasks

文献类型:期刊论文

作者Hongchang Zhai; Yu Y, Zhang W; Chen G; Fucang Jia
刊名Brain Imaging and Behavior
出版日期2016
英文摘要Cerebral glioma is one of the most aggressive space-occupying diseases, which will exhibit midline shift (MLS) due to mass effect. MLS has been used as an important feature for evaluating the pathological severity and patients’ survival possibility. Automatic quantification of MLS is challenging due to deformation, complex shape and complex grayscale distribution. An automatic method is proposed and validated to estimate MLS in patients with gliomas diagnosed using magnetic resonance imaging (MRI). The deformed midline is approximated by combining mechanical model and local symmetry. An enhanced Voigt model which takes into account the size and spatial information of lesion is devised to predict the deformed midline. A composite local symmetry combining local intensity symmetry and local intensity gradient symmetry is proposed to refine the predicted midline within a local window whose size is determined according to the pinhole camera model. To enhance the MLS accuracy, the axial slice with maximum MSL from each volumetric data has been interpolated from a spatial resolution of 1 mm to 0.33 mm. The proposed method has been validated on 30 publicly available clinical head MRI scans presenting with MLS. It delineates the deformed midline with maximum MLS and yields a mean difference of 0.61 ± 0.27 mm, and average maximum difference of 1.89 ± 1.18 mm from the ground truth. Experiments show that the proposed method will yield better accuracy with the geometric center of pathology being the geometric center of tumor and the pathological region being the whole lesion. It has also been shown that the proposed composite local symmetry achieves significantly higher accuracy than the traditional local intensity symmetry and the local intensity gradient symmetry. To the best of our knowledge, for delineation of deformed midline, this is the first report on both quantification of gliomas and from MRI, which hopefully will provide valuable information for diagnosis and therapy. The study suggests that the size of the whole lesion and the location of tumor (instead of edema or the sum of edema and tumor) are more appropriate to determine the extent of deformation. Composite local symmetry is recommended to represent the local symmetry around the deformed midline. The proposed method could be potentially used to quantify the severity of patients with cerebral gliomas and other brain pathology, as well as to approximate midsagittal surface for brain quantification.
收录类别SCI
原文出处http://link.springer.com/article/10.1007/s11682-015-9486-1
语种英语
源URL[http://ir.siat.ac.cn:8080/handle/172644/10375]  
专题深圳先进技术研究院_医工所
作者单位Brain Imaging and Behavior
推荐引用方式
GB/T 7714
Hongchang Zhai,Yu Y, Zhang W,Chen G,et al. ACC and IPL networks in the perception of the faces of parents during selective tasks[J]. Brain Imaging and Behavior,2016.
APA Hongchang Zhai,Yu Y, Zhang W,Chen G,&Fucang Jia.(2016).ACC and IPL networks in the perception of the faces of parents during selective tasks.Brain Imaging and Behavior.
MLA Hongchang Zhai,et al."ACC and IPL networks in the perception of the faces of parents during selective tasks".Brain Imaging and Behavior (2016).

入库方式: OAI收割

来源:深圳先进技术研究院

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