CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia.
文献类型：期刊论文
| 作者 | Ma, Dongli; Zhong, Shan; Liu, Xiaorong; Mai, Huirong; Mai, Guoqin; Xu, Cheng; Zhou, Fengfeng |
| 刊名 | COMPUTERS IN BIOLOGY AND MEDICINE
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| 出版日期 | 2016 |
| 英文摘要 | Different therapeutic methods have been developed for the B-cell and T-cell subtypes of acute lymphoblastic leukemia (ALL). The identification of molecular biomarkers that can accurately discriminate between B-cell and T-cell ALLs will facilitate the quick determination of therapeutic plans, as well as reveal the intrinsic mechanisms underlining the two different ALL subtypes. This study computationally screened the high-throughput transcriptome dataset for multiple candidate biomarkers and verified their discrimination abilities in an independent sample set using quantitative real-time polymerase chain reaction (PCR) technology. Both technologies suggest that the two genes CD3D and PKRCQ together provided a good model for classification of B-cell and T-cell ALLs, whereas the individual genes did not show consistent discrimination between the two ALL subtypes. Supplementary material is available at http://healthinformaticslab.org/supp/. |
| 收录类别 | SCI |
| 原文出处 | http://www.sciencedirect.com/science/article/pii/S0010482516301809 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/10404]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | COMPUTERS IN BIOLOGY AND MEDICINE |
| 推荐引用方式 GB/T 7714 | Ma, Dongli,Zhong, Shan,Liu, Xiaorong,et al. CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia.[J]. COMPUTERS IN BIOLOGY AND MEDICINE,2016. |
| APA | Ma, Dongli.,Zhong, Shan.,Liu, Xiaorong.,Mai, Huirong.,Mai, Guoqin.,...&Zhou, Fengfeng.(2016).CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia..COMPUTERS IN BIOLOGY AND MEDICINE. |
| MLA | Ma, Dongli,et al."CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia.".COMPUTERS IN BIOLOGY AND MEDICINE (2016). |
入库方式： OAI收割
来源：深圳先进技术研究院
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