Engineering of porous bacterial cellulose toward human fibroblasts ingrowth for tissue engineering
文献类型：期刊论文
| 作者 | Hu, Yang; Catchmark, Jeffrey M.; Zhu, Yongjun; Abidi, Noureddine; Zhou, Xin; Wang, Jinhui; Liang, Nuanyi |
| 刊名 | JOURNAL OF MATERIALS RESEARCH
 |
| 出版日期 | 2014 |
| 英文摘要 | From the view of tissue engineering, the deficiency in porosity has impeded further application of bacterial cellulose (BC) as a super biomaterial. In this study, we used a combination method consisting of acetic acid treatment and freeze-drying operation to improve the porous profile of BC, as well as a simple and fast method to measure the thickness, density, and porosity of BC. Results have shown a significant improvement in the porosity of the inner structure of BC treated with acetic acid and freeze-drying. Microscopic observation by scanning electron microscopy exhibited explicit evidences that more orderly porouslayer-by-layer structures and more pores were formed along the cross section of modified BC as compared with the control. The enhancement of mechanical properties and crystallinity of modified BC was also demonstrated due to the improvement of material porosity in the particular extent from 50.3 to 76.43%. Cell culture of human fibroblast cells exhibited good cell viability on modified BC, suggesting that a better porous profile of BC on the surface and cross section helps facilitate cells to attach, as well as potentially promotes cells to grow in. These significant results may open the possibility of producing BC nanomaterials for tissue engineering with desirable properties. |
| 收录类别 | SCI |
| 原文出处 | http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=9421201&fileId=S088429141400315X |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/6097]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | JOURNAL OF MATERIALS RESEARCH |
| 推荐引用方式 GB/T 7714 | Hu, Yang,Catchmark, Jeffrey M.,Zhu, Yongjun,et al. Engineering of porous bacterial cellulose toward human fibroblasts ingrowth for tissue engineering[J]. JOURNAL OF MATERIALS RESEARCH,2014. |
| APA | Hu, Yang.,Catchmark, Jeffrey M..,Zhu, Yongjun.,Abidi, Noureddine.,Zhou, Xin.,...&Liang, Nuanyi.(2014).Engineering of porous bacterial cellulose toward human fibroblasts ingrowth for tissue engineering.JOURNAL OF MATERIALS RESEARCH. |
| MLA | Hu, Yang,et al."Engineering of porous bacterial cellulose toward human fibroblasts ingrowth for tissue engineering".JOURNAL OF MATERIALS RESEARCH (2014). |
入库方式： OAI收割
来源：深圳先进技术研究院
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