Intervention timing of strontium treatment on estrogen depletion‐induced osteoporosis in rats: Bone microstructure and mechanics
文献类型:期刊论文
作者 | Peng, Songlin; Liu, X. Sherry; Huang, Shishu; Pan, Haobo; Zhen, Wanxin; Zhou, Guangqian; Luk, K. D. K.; Guo, X. Edward; Lu, W. William |
刊名 | JOURNAL OF ORTHOPAEDIC RESEARCH
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出版日期 | 2014 |
英文摘要 | MethodsNinety female rats were randomly divided into three batches with three groups in each batch. Each group was divided according to the initiation timingof vehicle or strontium compound (SrC), which was at week 0 (early), 4 (mid-term) and 8 (late) after the ovariectomy, respectively. The treatment lasted for 12 weeks. The trabecular bone biomechanical properties, trabecular bone tissue mechanical properties, trabecular bone microstructure, and bone remodeling were analyzed with mechanical testing, nanoindentation, microCT, and histomorphometry, respectively. The osteoblast and osteoclast phenotypic genes were analyzed with real-time polymerase chain reaction (PCR). |
收录类别 | SCI |
原文出处 | http://onlinelibrary.wiley.com/doi/10.1002/jor.22517/full |
语种 | 英语 |
源URL | [http://ir.siat.ac.cn:8080/handle/172644/6101] ![]() |
专题 | 深圳先进技术研究院_医药所 |
作者单位 | JOURNAL OF ORTHOPAEDIC RESEARCH |
推荐引用方式 GB/T 7714 | Peng, Songlin,Liu, X. Sherry,Huang, Shishu,et al. Intervention timing of strontium treatment on estrogen depletion‐induced osteoporosis in rats: Bone microstructure and mechanics[J]. JOURNAL OF ORTHOPAEDIC RESEARCH,2014. |
APA | Peng, Songlin.,Liu, X. Sherry.,Huang, Shishu.,Pan, Haobo.,Zhen, Wanxin.,...&Lu, W. William.(2014).Intervention timing of strontium treatment on estrogen depletion‐induced osteoporosis in rats: Bone microstructure and mechanics.JOURNAL OF ORTHOPAEDIC RESEARCH. |
MLA | Peng, Songlin,et al."Intervention timing of strontium treatment on estrogen depletion‐induced osteoporosis in rats: Bone microstructure and mechanics".JOURNAL OF ORTHOPAEDIC RESEARCH (2014). |
入库方式: OAI收割
来源:深圳先进技术研究院
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