中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Characterisation and immunomodulating activities of exo-polysaccharides from submergedcultivation of Hypsizigus marmoreus

文献类型:期刊论文

作者Zhang, Bing-Zhao; Inngjerdingen, Kari T.; Zou, Yuan-Feng; Rise, Frode; Michaelsen, Terje E.; Yan, Pei-Sheng; Paulsen, Berit S.
刊名FOOD CHEMISTRY
出版日期2014
英文摘要Exo-polysaccharides were purified and characterized from the fermentation broth of Hypsizigus marmoreus, a popular edible mushroom consumed in Asia. Among them, B-I-I and B-II-I exhibited potent complement fixating activity, meanwhile, B-N-I, B-II-I and B-II-II exhibited significant macrophage stimulating activity. Molecular weights of the four exo-polysaccharides were determined to be 6.3, 120, 150 and 11 kDa respectively. Molecular characterisation showed that B-N-I is basically an alpha-1 -> 4 glucan, with branches on C-6; B-I-I is a heavily branched a-mannan with 1 -> 2 linked main chain. B-II-I and B-II-II, have a backbone of rhamno-galacturonan with 1 -> 2 linked L-rhamnose interspersed with 1 -> 4 linked galacturonic acid. Structure-activity relationship analysis indicated that monosaccharide compositions, molecular weight, certain structural units (rhamno-galacturonan type I and arabinogalactan type II) are the principal factors responsible for potent complement fixating and macrophage-stimulating activities. Their immunomodulating activities may, at least partly, explain the health benefits of the mushroom. (C) 2014 Elsevier Ltd. All rights reserved.
收录类别SCI
原文出处http://www.sciencedirect.com/science/article/pii/S0308814614006621
语种英语
源URL[http://ir.siat.ac.cn:8080/handle/172644/6111]  
专题深圳先进技术研究院_医药所
作者单位FOOD CHEMISTRY
推荐引用方式
GB/T 7714
Zhang, Bing-Zhao,Inngjerdingen, Kari T.,Zou, Yuan-Feng,et al. Characterisation and immunomodulating activities of exo-polysaccharides from submergedcultivation of Hypsizigus marmoreus[J]. FOOD CHEMISTRY,2014.
APA Zhang, Bing-Zhao.,Inngjerdingen, Kari T..,Zou, Yuan-Feng.,Rise, Frode.,Michaelsen, Terje E..,...&Paulsen, Berit S..(2014).Characterisation and immunomodulating activities of exo-polysaccharides from submergedcultivation of Hypsizigus marmoreus.FOOD CHEMISTRY.
MLA Zhang, Bing-Zhao,et al."Characterisation and immunomodulating activities of exo-polysaccharides from submergedcultivation of Hypsizigus marmoreus".FOOD CHEMISTRY (2014).

入库方式: OAI收割

来源:深圳先进技术研究院

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