Competitive reaction pathway for site-selective conjugation of Raman dyes to hotspots on gold nanorods for greatly enhanced SERS performance
文献类型：期刊论文
| 作者 | Huang, Hao; Wang, Jia-Hong; Jin, Weihong; Li, Penghui; Chen, Ming; Xie, Han-Han; Yu, Xue-Feng; Wang, Huaiyu; Dai, Zhigao; Xiao, XianghengChu, Paul K. |
| 刊名 | SMALL
 |
| 出版日期 | 2014 |
| 英文摘要 | Common methods to prepare SERS (surface-enhanced Raman scattering) probes rely on random conjugation of Raman dyes onto metal nanostructures, but most of the Raman dyes are not located at Raman-intense electromagnetic hotspots thus not contributing to SERS enhancement substantially. Herein, acompetitive reaction between transverse gold overgrowth and dye conjugation is described to achieve site selective conjugation of Raman dyes to the hotspots(ends) on gold nanorods (GNRs). The preferential overgrowth on the nanorod side surface creates a barrier to prevent the Raman dyes from binding to the side surface except the ends of the GNRs, where the highest SERS enhancement factors are expected. The SERS enhancement observed from this special structure is dozens of times larger than that from conjugates synthesized by conventional methods. This simple and powerful strategy to prepare SERS probes can be extended to different anisotropic metal nanostructures with electromagnetic hotspots and has immense potential in in-depth SERS-based biological imaging and single-molecule detection. |
| 收录类别 | SCI |
| 原文出处 | http://onlinelibrary.wiley.com/doi/10.1002/smll.201400860/abstract |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/6121]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | SMALL |
| 推荐引用方式 GB/T 7714 | Huang, Hao,Wang, Jia-Hong,Jin, Weihong,et al. Competitive reaction pathway for site-selective conjugation of Raman dyes to hotspots on gold nanorods for greatly enhanced SERS performance[J]. SMALL,2014. |
| APA | Huang, Hao.,Wang, Jia-Hong.,Jin, Weihong.,Li, Penghui.,Chen, Ming.,...&Xiao, XianghengChu, Paul K..(2014).Competitive reaction pathway for site-selective conjugation of Raman dyes to hotspots on gold nanorods for greatly enhanced SERS performance.SMALL. |
| MLA | Huang, Hao,et al."Competitive reaction pathway for site-selective conjugation of Raman dyes to hotspots on gold nanorods for greatly enhanced SERS performance".SMALL (2014). |
入库方式： OAI收割
来源：深圳先进技术研究院
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