Triphosgene-Mediated Couplings in the Solid Phase: Total Synthesis of Brachystemin A
文献类型:期刊论文
作者 | Fang, Lijing; Wu, Chunlei; Yu, Zaidan; Shang, Peng; Cheng, Yongxian; Peng, Yuefeng; Su, Wu |
刊名 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
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出版日期 | 2014 |
英文摘要 | A reproducible, highly efficient, and racemization-free protocol for the triphosgene-mediated solid-phase coupling of proteinogenic amino acids was developed.The efficiency of the reaction was demonstrated by the first total synthesis of the bioactive natural octacyclopeptide brachystemin A. This protocol will broadenthe application of triphosgene in the synthesis of a wide range of peptides, including aromatic amino acids, N-alkylated amino acids, as well as proteinogenic amino acids. |
收录类别 | SCI |
原文出处 | http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201403145/abstract |
语种 | 英语 |
源URL | [http://ir.siat.ac.cn:8080/handle/172644/6143] ![]() |
专题 | 深圳先进技术研究院_医药所 |
作者单位 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
推荐引用方式 GB/T 7714 | Fang, Lijing,Wu, Chunlei,Yu, Zaidan,et al. Triphosgene-Mediated Couplings in the Solid Phase: Total Synthesis of Brachystemin A[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2014. |
APA | Fang, Lijing.,Wu, Chunlei.,Yu, Zaidan.,Shang, Peng.,Cheng, Yongxian.,...&Su, Wu.(2014).Triphosgene-Mediated Couplings in the Solid Phase: Total Synthesis of Brachystemin A.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. |
MLA | Fang, Lijing,et al."Triphosgene-Mediated Couplings in the Solid Phase: Total Synthesis of Brachystemin A".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2014). |
入库方式: OAI收割
来源:深圳先进技术研究院
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