Fully Automated Synthesis of DNA-Binding Py-Im Polyamides Using a Triphosgene Coupling Strategy
文献类型：期刊论文
| 作者 | Lijing Fang; Guiyang Yao; Zhengyin Pan; Chunlei Wu; Heng-Shan Wang; Glenn A Burley; Wu Su |
| 刊名 | Organic Letters
 |
| 出版日期 | 2015 |
| 英文摘要 | The fully automated solid-phase synthetic strategy of hairpin pyrrole−imidazole polyamides is described. A key advance is the development of methodology for the application of triphosgene as a coupling agent in the automated synthesis of hairpin polyamides without racemization. This automated methodology is compatible with all the typical building blocks, enabling the facile synthesis of polyamide libraries in good yield (9−15%) and crude purity. |
| 收录类别 | SCI |
| 原文出处 | http://pubs.acs.org/doi/pdf/10.1021/ol503388a |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7340]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | Organic Letters |
| 推荐引用方式 GB/T 7714 | Lijing Fang,Guiyang Yao,Zhengyin Pan,et al. Fully Automated Synthesis of DNA-Binding Py-Im Polyamides Using a Triphosgene Coupling Strategy[J]. Organic Letters,2015. |
| APA | Lijing Fang.,Guiyang Yao.,Zhengyin Pan.,Chunlei Wu.,Heng-Shan Wang.,...&Wu Su.(2015).Fully Automated Synthesis of DNA-Binding Py-Im Polyamides Using a Triphosgene Coupling Strategy.Organic Letters. |
| MLA | Lijing Fang,et al."Fully Automated Synthesis of DNA-Binding Py-Im Polyamides Using a Triphosgene Coupling Strategy".Organic Letters (2015). |
入库方式： OAI收割
来源：深圳先进技术研究院
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