Efficient Synthesis and Stereochemical Revision of Coibamide A
文献类型：期刊论文
| 作者 | Guiyang Yao; Zhengyin Pan; Chunlei Wu; Wei Wang; Lijing Fang; Wu Su |
| 刊名 | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
 |
| 出版日期 | 2015 |
| 英文摘要 | Coibamide A is a highly potent antiproliferalive cyclodepsipeptide originally isolated from a Panamanian marine cyanobacterium. Herein we report anefficient solid-phase strategy for assembly of highly N-methylated cyclodepsipeptides, which is invaluable in generating coibamide A derivatives for structure-activity relationship studies. As a consequence of our synthetic studies, two stereochemical assignments of coibamide A were revised and the total synthesis of this natural compound was achieved for the first time. |
| 收录类别 | SCI |
| 原文出处 | http://pubs.acs.org/doi/abs/10.1021/jacs.5b09286 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7358]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
| 推荐引用方式 GB/T 7714 | Guiyang Yao,Zhengyin Pan,Chunlei Wu,et al. Efficient Synthesis and Stereochemical Revision of Coibamide A[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2015. |
| APA | Guiyang Yao,Zhengyin Pan,Chunlei Wu,Wei Wang,Lijing Fang,&Wu Su.(2015).Efficient Synthesis and Stereochemical Revision of Coibamide A.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. |
| MLA | Guiyang Yao,et al."Efficient Synthesis and Stereochemical Revision of Coibamide A".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015). |
入库方式： OAI收割
来源：深圳先进技术研究院
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