The efficient hemostatic effect of Antarctic krill chitosan is related toits hydration property
文献类型：期刊论文
| 作者 | Shuai Wu; Zhuoyao Huang; Jianhui Yue; Di Liu; Ting Wang; Pierre Ezanno; Changshun Ruan; Xiaoli Zhao; William W. Lu; Haobo Pan |
| 刊名 | Carbohydrate Polymers
 |
| 出版日期 | 2015 |
| 英文摘要 | tAntarctic krill chitosan (A-Chitosan) was first evaluated in its hemostatic effect in this study. The preparedA-Chitosan powder showed low level of crystallinity and significantly high water binding capacity as1293% (w/w). By mice tail amputation model and blood coagulation timing experiment, it is showedthat this chitosan accelerated the tail hemostasis by 55% and shortened the blood clotting time by 38%.This efficacy was better than two other commercial chitosans investigated and was corresponding totheir water binding capacities. Through examining the effect of chitosan on blood components, it couldbe found that platelets adhesion was mainly affected by the water binding capacity, and red blood cellsaggregation was dependent on their deacetylation degree. The physicochemical properties resulted inbetter hydration property of chitosan would improve its hemostatic effect. These results suggested thatAntarctic krill chitosan is a good candidate for hemostatic application. |
| 收录类别 | SCI |
| 原文出处 | http://www.sciencedirect.com/science/article/pii/S0144861715005354 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7387]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | Carbohydrate Polymers |
| 推荐引用方式 GB/T 7714 | Shuai Wu,Zhuoyao Huang,Jianhui Yue,et al. The efficient hemostatic effect of Antarctic krill chitosan is related toits hydration property[J]. Carbohydrate Polymers,2015. |
| APA | Shuai Wu.,Zhuoyao Huang.,Jianhui Yue.,Di Liu.,Ting Wang.,...&Haobo Pan.(2015).The efficient hemostatic effect of Antarctic krill chitosan is related toits hydration property.Carbohydrate Polymers. |
| MLA | Shuai Wu,et al."The efficient hemostatic effect of Antarctic krill chitosan is related toits hydration property".Carbohydrate Polymers (2015). |
入库方式： OAI收割
来源：深圳先进技术研究院
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